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- Table of Contents
Facts about Heat shock protein beta-6.
Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR.
Human | |
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Gene Name: | HSPB6 |
Uniprot: | O14558 |
Entrez: | 126393 |
Belongs to: |
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small heat shock protein (HSP20) family |
FLJ32389; Heat shock 20 kDa-like protein p20; heat shock protein beta-6; heat shock protein, alpha-crystallin-related, B6; HSP20; HSPB6
Mass (kDA):
17.136 kDA
Human | |
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Location: | 19q13.12 |
Sequence: | 19; NC_000019.10 (35754566..35757029, complement) |
Cytoplasm. Nucleus. Secreted. Translocates to nuclear foci during heat shock.
PMID: 8195168 by Kato K., et al. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.
PMID: 19845507 by Fuchs M., et al. Identification of the key structural motifs involved in HspB8/HspB6- Bag3 interaction.