HSD17B6 Antibodies

AND HSD17B6 ELISA kits, HSD17B6 Proteins

Many biological assays use antibodies to detect HSD17B6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B6 antibodies...

We validate the specificity of these antibodies to HSD17B6 by testing them on tissues known to express HSD17B6 positively and negatively. Browse below to find the HSD17B6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: RNASET2

HSD17B6 Infographic by Boster Bio

All HSD17B6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HSD17B6 Antibody Picoband®

4 Q&As

Human

IHC, WB

$370
Cat # PA1386
100 μg/vial

HSD17B6 (NM_003725) Human Over-expression Lysate

Human

$628
Cat # LS008630
100 µg

HSD17B6 Overview

Facts about 17-beta-hydroxysteroid dehydrogenase type 6.

HSD17B6 3D structure. Source: alphafold

17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6)

NAD-dependent oxidoreductase with broad substrate specificity that reveals both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro).

Converts 5-alpha-androstan-3- alpha,17-beta-diol into androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro).

Gene Information

Human
Gene Name:	HSD17B6
Uniprot:	O14756
Entrez:	8630

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

17-beta-HSD 6; 17-beta-HSD6; 17-beta-hydroxysteroid dehydrogenase type 6; 3(alpha->beta)-hydroxysteroid epimerase; 3-alpha->beta-HSE; EC 1.1.1; EC 1.1.1.105; EC 1.1.1.62; EC 1.1.1.63; HSE3-hydroxysteroid epimerase; hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse); hydroxysteroid (17-beta) dehydrogenase 6; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase; Oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; oxidoreductase; retinol dehydrogenase; RODH3(alpha->beta)-hydroxysteroid epimerasel; SDR9C6; short

Molecular Weight

Mass (kDA):
35.966 kDA

Genomic Context


Human

Location:	12q13.3
Sequence:	12; NC_000012.12 (56752449..56787790)

Tissue Specificity

Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.

Subcellular Localizations

Microsome membrane; Peripheral membrane protein; Lumenal side. Early endosome membrane; Peripheral membrane protein; Lumenal side.

Diseases

Polycystic Ovary Syndrome
Insulin Resistance
Cholangiocarcinoma
Malignant Neoplasm Of Prostate
Prostatic Hyperplasia
Endometrial Polyp
Benign Prostatic Hypertrophy
Leg Ulcer
Ulcer
Endometriosis, Site Unspecified

Malignant Neoplasms
Prostatic Neoplasms
Varicose Ulcer
Hyperplasia

Pathways

Wound Healing
Menarche
Localization

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B6

References

PMID: 9188497 by Biswas M.G., et al. Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.

PMID: 10896656 by Huang X.-F., et al. Molecular characterization of a first human 3(alpha-->beta)- hydroxysteroid epimerase.