HSD17B14 Antibodies

AND HSD17B14 ELISA kits, HSD17B14 Proteins

Many biological assays use antibodies to detect HSD17B14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B14 antibodies...

We validate the specificity of these antibodies to HSD17B14 by testing them on tissues known to express HSD17B14 positively and negatively. Browse below to find the HSD17B14 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HSD17B14 Infographic by Boster Bio

All HSD17B14 Products

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Product

Figures

Specificity

Applications

Price

Anti-DHB14 HSD17B14 Antibody

Human

ELISA, WB

$380
Cat # A13289
100ul

Human 17 beta -HSD14/HSD17B14 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9BPX1
Starting from 20ug

HSD17B14 (NM_016246) Human Over-expression Lysate

Human

$628
Cat # LS051171
100 µg

HSD17B14 Overview

Facts about 17-beta-hydroxysteroid dehydrogenase 14.

HSD17B14 3D structure. Source: alphafold

17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14)

Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone.

The physiological substrate isn't known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro).

Gene Information

Human
Gene Name:	HSD17B14
Uniprot:	Q9BPX1
Entrez:	51171

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

17 betaHSD14; 17 beta-HSD14; dehydrogenase/reductase (SDR family) member 10; Dehydrogenase/reductase SDR family member 10; DHRS10; DHRS1017-beta-hydroxysteroid dehydrogenase 14; EC 1.1.1.-; HSD17B14; hydroxysteroid (17-beta) dehydrogenase 14,17-beta-hydroxysteroid dehydrogenase DHRS10; retinal short-chain dehydrogenase/reductase 3; Retinal short-chain dehydrogenase/reductase retSDR3; retSDR3; RETSDR3,17-beta-HSD 14; SDR3; SDR47C1; short chain dehydrogenase/reductase family 47C, member 1

Molecular Weight

Mass (kDA):
28.317 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (48813014..48836688, complement)

Tissue Specificity

Highly expressed in brain, placenta, liver and kidney.

Subcellular Localizations

Cytoplasm.

Diseases

Nervousness

Interacting Proteins

CA8
CDKN2D
DDIT3
MPG
NEK6

NUDT18
PHF1
SNAPC3
SREK1IP1
TBC1D22B

WDYHV1

Pathways

Localization
Secretion

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B14

References

PMID: 10800688 by Haeseleer F., et al. Short-chain dehydrogenases/reductases in retina.

PMID: 17067289 by Lukacik P., et al. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.