HRK Antibodies

AND HRK ELISA kits, HRK Proteins

Many biological assays use antibodies to detect HRK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HRK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HRK antibodies...

We validate the specificity of these antibodies to HRK by testing them on tissues known to express HRK positively and negatively. Browse below to find the HRK antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HRK Infographic by Boster Bio

All HRK Products

Product

Figures

Specificity

Applications

Price

Anti-Hrk Antibody

Human, Mouse

ELISA, WB

$449
Cat # A09125
0.1 mg

Anti-HRK Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09125-1
100ul

HRK (NM_003806) Human Over-expression Lysate

Human

$628
Cat # LS008739
100 µg

HRK Overview

Facts about Activator of apoptosis harakiri.

HRK 3D structure. Source: alphafold

Activator of apoptosis harakiri (HRK)

Promotes apoptosis. .

Gene Information

Human
Gene Name:	HRK
Uniprot:	O00198
Entrez:	8739

Family

Belongs to:

No superfamily

Alternative Names

activator of apoptosis harakiri; activator of apoptosis Hrk; BCL2-interacting protein; BH3-interacting domain-containing protein 3; BID3; death protein 5; DP5; HARAKIRI; harakiri, BCL2 interacting protein (contains only BH3 domain); harakiri, BCL2-interacting protein (contains only BH3 domain); Hrk; Neuronal death protein DP5

Molecular Weight

Mass (kDA):
9.884 kDA

Genomic Context


Human

Location:	12q24.22
Sequence:	12; NC_000012.12 (116856144..116881441, complement)

Subcellular Localizations

Membrane; Single-pass membrane protein. Mitochondrion.

Diseases

Malignant Neoplasms
Neoplasms
Nervousness
Lymphoma
Diabetes Mellitus
Mammary Neoplasms
Inflammation
Atrophy
Prostatic Neoplasms
Malignant Neoplasm Of Ovary
Malignant Neoplasm Of Breast
Diabetes Mellitus, Insulin-dependent
Cell Transformation, Neoplastic

Glioblastoma
Leukemia
Astrocytoma
Melanoma
Immunologic Deficiency Syndromes
Ovarian Neoplasm
Central Nervous System Neoplasms

Interacting Proteins

C1QBP

Pathways

Cell Death
Methylation
Programmed Cell Death
Induction Of Apoptosis
Localization
Autophagy
Immune Response
Embryo Development
Cell Proliferation
Dna Methylation
Cell Growth
Rna Interference
Gene Silencing

Cell Cycle
Dna Repair
Pathogenesis
Apoptotic Process
Tissue Homeostasis
Mammary Gland Involution
Mitochondrial Outer Membrane Permeabilization

PTMs

Phosphorylation
Methylation

Cleavage
Nitration

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HRK

References

PMID: 9130713 by Inohara N., et al. Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).

PMID: 15031724 by Sunayama J., et al. Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32.