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- Table of Contents
Facts about Histamine H4 receptor.
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Human | |
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Gene Name: | HRH4 |
Uniprot: | Q9H3N8 |
Entrez: | 59340 |
Belongs to: |
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G-protein coupled receptor 1 family |
AXOR35; AXOR35H4; BG26; GPCR105; GPCR105MGC133027; G-protein coupled receptor 105; GPRv53; GPRv53histamine H4 receptor; H4Rpfi-013; HH4R; HH4RBG26; Histamine H4 R; Histamine H4R; histamine receptor H4; HRH4; Pfi-013; SP9144
Mass (kDA):
44.496 kDA
Human | |
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Location: | 18q11.2 |
Sequence: | 18; NC_000018.10 (24460637..24479974) |
Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node.
Cell membrane; Multi-pass membrane protein.
PMID: 10973974 by Oda T., et al. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes.
PMID: 11118334 by Nakamura T., et al. Molecular cloning and characterization of a new human histamine receptor, HH4R.