HPRT1 Antibodies

AND HPRT1 ELISA kits, HPRT1 Proteins

Many biological assays use antibodies to detect HPRT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPRT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPRT1 antibodies...

We validate the specificity of these antibodies to HPRT1 by testing them on tissues known to express HPRT1 positively and negatively. Browse below to find the HPRT1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HPRT1 Infographic by Boster Bio

All HPRT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HPRT/HPRT1 Antibody Picoband®

5 Q&As

Human, Mouse, Rat

$370
Cat # PB10071
100 μg/vial

Anti-HPRT HPRT1 Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M00668
100 μl

Anti-HPRT HPRT1 Antibody

Human, Mouse, Rat, Zebrafish

IP, IHC, WB

$405
Cat # A00668
100ul

Human HPRT1 Recombinant Protein

SDS-PAGE

$243
Cat # PROTP00492
Starting from 20ug

HPRT (HPRT1) (NM_000194) Human Over-expression Lysate

Human

$628
Cat # LS003251
100 µg

Anti-HPRT1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00668-1
100 µg/vial

HPRT1 Overview

Facts about Hypoxanthine-guanine phosphoribosyltransferase.

HPRT1 3D structure. Source: alphafold

Hypoxanthine-guanine phosphoribosyltransferase (HPRT1)

Converts guanine into guanosine monophosphate, and hypoxanthine into inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.

Plays a central role in the generation of purine nucleotides through the purine salvage pathway. .

Gene Information

Human
Gene Name:	HPRT1
Uniprot:	P00492
Entrez:	3251

Family

Belongs to:

purine/pyrimidine phosphoribosyltransferase family

Alternative Names

EC 2.4.2.8; HGPRT; HGPRT1; HGPRTHPRTHGPRTase; HPRT; HPRT1; hypoxanthine phosphoribosyltransferase 1; hypoxanthine-guanine phosphoribosyltransferase

Molecular Weight

Mass (kDA):
24.579 kDA

Genomic Context


Human

Location:	Xq26.2-q26.3
Sequence:	X; NC_000023.11 (134460165..134500668)

Subcellular Localizations

Cytoplasm.

Diseases

Lesch-nyhan Syndrome
Neoplasms
Malignant Neoplasms
Carcinoma
Hyperuricemia
Gout
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Lung
Obesity
Kidney Neoplasm
Mammary Neoplasms
Lung Neoplasms

Hepatitis
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Non-small Cell Lung Carcinoma
Malignant Neoplasm Of Breast
Renal Cell Carcinoma
Liver Carcinoma

Interacting Proteins

ISCU
PRTFDC1
SDCBP
WDYHV1

Pathways

Reverse Transcription
Regeneration
Aging
Dosage Compensation
Embryo Development
Cell Proliferation
Methylation
Pathogenesis
Gene Silencing
Osteoblast Differentiation
Fertilization
Immune Response
Inflammatory Response

Chemotaxis
Mrna Splicing
Mrna Transcription
Translation
Cell Cycle
Cell Differentiation
Liver Regeneration

PTMs

Methylation

Cleavage

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPRT1

References

PMID: 6300847 by Jolly D.J., et al. Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

PMID: 2341149 by Edwards A., et al. Automated DNA sequencing of the human HPRT locus.