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HPS1 Antibodies

AND HPS1 ELISA kits, HPS1 Proteins

Many biological assays use antibodies to detect HPS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPS1 antibodies...

We validate the specificity of these antibodies to HPS1 by testing them on tissues known to express HPS1 positively and negatively. Browse below to find the HPS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HPS1 Infographic by Boster Bio

HPS1 protein infographic

All HPS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HPS-1 Monoclonal Antibody

13 Q&As

Human

WB

$399
Cat # A05026
100μl

Anti-HPS1 Antibody

Human, Mouse, Rat

IF, ICC

$405
Cat # A05026-1
100ul

HPS1 (NM_182639) Human Recombinant Protein

$1062
Cat # PROTQ92902
20 µg

HPS1 Overview

Facts about Hermansky-Pudlak syndrome 1 protein.

HPS1 3D structure

HPS1 3D structure. Source: alphafold

Hermansky-Pudlak syndrome 1 protein (HPS1)

Part of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an energetic GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and boosts the membrane localization of RAB32 and RAB38 (PubMed:23084991).

.

Gene Information

Human
Gene Name:	HPS1
Uniprot:	Q92902
Entrez:	3257

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

Hermansky-Pudlak syndrome 1 protein; Hermansky-Pudlak syndrome 1; Hermansky-Pudlak syndrome type 1; Hermansky-Pudlak syndrome; HPS; MGC5277

Molecular Weight

Mass (kDA):
79.292 kDA

Molecular Weight

Genomic Context


Human

Location:	10q24.2
Sequence:	10; NC_000010.11 (98416193..98446963, complement)

Tissue Specificity

Ubiquitous.

Diseases

Hermanski-pudlak Syndrome
Albinism, Oculocutaneous
Albinism
Hemorrhage
Fibrosis
Pulmonary Fibrosis
Bleeding Tendency
Platelet Storage Pool Deficiency
Hypopigmentation Disorder
Colitis
Crohn's Disease Of Large Bowel
Hereditary Diseases

Mycoplasma Pneumonia
Lung Diseases
Pneumonia
Inflammation
Melanoma
Nystagmus
Lung Diseases, Interstitial

Disease

Interacting Proteins

HPS4

Interacting Proteins

Pathways

Pigmentation
Secretion
Transport
Localization
Membrane Fusion
Vesicle Docking
Pathogenesis
Proteolysis
Gluconeogenesis
Platelet Activation
Serotonin Uptake
Spermatogenesis
Inflammatory Response

Platelet Aggregation
Chemokine Secretion
Chemotaxis
Reverse Transcription
Interphase
Response To Nutrient
Hemostasis

Pathways

PTMs

Phosphorylation

Nitrosylation

Glycosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPS1

References

PMID: 8896559 by Oh J., et al. Positional cloning of a gene for Hermansky-Pudlak syndrome, a disorder of cytoplasmic organelles.

PMID: 9182823 by Bailin T., et al. Organization and nucleotide sequence of the human Hermansky-Pudlak syndrome (HPS) gene.