Homer protein homolog 1 Antibodies

AND HOMER1 ELISA kits, Homer protein homolog 1 Proteins

Many biological assays use antibodies to detect Homer protein homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homer protein homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homer protein homolog 1 antibodies...

We validate the specificity of these antibodies to Homer protein homolog 1 by testing them on tissues known to express HOMER1 positively and negatively. Browse below to find the HOMER1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HOMER1 Infographic by Boster Bio

All HOMER1 Products

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Product

Figures

Specificity

Applications

Price

Anti-HOME1 HOMER1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A03877
100ul

Human HOMER1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ86YM7
Starting from 20ug

Anti-HOMER1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03877-1
100 μg/vial

Anti-HOMER1 Mouse Monoclonal Antibody [Clone ID: OTI7G10]

Human, Mouse, Rat

IHC, WB

$523
Cat # M03877
100 µl

Anti-Homer1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M03877-1
100 μl/vial

HOMER1 (NM_004272) Human Over-expression Lysate

Human

$628
Cat # LS009456
100 µg

HOMER1 Overview

Facts about Homer protein homolog 1.

HOMER1 3D structure. Source: alphafold

Homer protein homolog 1 (HOMER1)

Binds and cross-links cytoplasmic areas of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.

May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5.

Gene Information

Human
Gene Name:	HOMER1
Uniprot:	Q86YM7
Entrez:	9456

Family

Belongs to:

Homer family

Alternative Names

homer homolog 1 (Drosophila); HOMER; HOMER1; homer-1; HOMER1A; HOMER1B; HOMER-1B; HOMER1C; SYN47; SYN47neuronal immediate early gene, 1; Ves-1

Molecular Weight

Mass (kDA):
40.277 kDA

Genomic Context


Human

Location:	5q14.1
Sequence:	5; NC_000005.10 (79372636..79514134, complement)

Subcellular Localizations

Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cell projection, dendritic spine. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the endoplasmic reticulum.

Diseases

Pain
Depressive Disorder
Stress, Psychological
Neuralgia
Hyperalgesia
Parkinson Disease
Nervousness
Peripheral Nerve Injuries
Psychotic Disorders
Mood Disorders
Secondary Parkinson Disease
Nerve Damage

Nerve Degeneration
Schizophrenia
Thermal Hyperalgesia
Alzheimer's Disease
Anhedonia
Cholangiocarcinoma

Interacting Proteins

ABI3
C19orf57
HOMER3
SARG
TRAF5

Pathways

Synaptic Transmission
Localization
Neurogenesis
Sensitization
Transport
Aging
Cognition
Pathogenesis
Secretion
Protein Phosphorylation
Synapse Maturation
Electron Transport
Regulation Of Signal Transduction

Brain Development
Membrane Organization
Muscle Contraction
Hypersensitivity
Platelet Aggregation
Reverse Transcription
Membrane Depolarization

PTMs

Phosphorylation
Deacetylation

Cleavage
Acetylation

Methylation

Research Areas

Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HOMER1

References

PMID: 9808458 by Xiao B., et al. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

PMID: 10464340 by Roche K.W., et al. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors.