HNRNPF Antibodies

Heterogeneous nuclear ribonucleoprotein F (HNRNPF)

Part of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes that provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events.

Binds G-rich sequences in pre-mRNAs and retains target RNA in an unfolded state. .

Gene Information

Human
Gene Name:	HNRNPF
Uniprot:	P52597
Entrez:	3185

Family

Belongs to:
No superfamily

Alternative Names

heterogeneous nuclear ribonucleoprotein F; hnRNP F; HNRPFHnRNP F protein; mcs94-1; MGC110997; Nucleolin-like protein mcs94-1; OK/SW-cl.23

Molecular Weight

Mass (kDA):
45.672 kDA

Genomic Context

Human
Location:	10q11.21
Sequence:	10; NC_000010.11 (43385617..43409248, complement)

Tissue Specificity

Expressed ubiquitously.

Subcellular Localizations

Nucleus, nucleoplasm.

Diseases

• Neoplasms
• Liver Carcinoma
• Nervousness
• Liver Neoplasms
• Hepatocarcinogenesis
• Carcinoma

Interacting Proteins

• AES
• C1orf94
• DZIP3
• EIF4ENIF1
• HNRNPM

• HNRNPUL1
• HSFY1
• IKZF3
• RBFOX2
• TFG

Pathways

• Rna Processing

PTMs

• Acetylation
• Isopeptide bond

• Phosphoprotein
• Ubl conjugation

Research Areas

• DNA Repair
• DNA replication, Transcription, Translation and Splicing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPF

Best Uses Of The HNRNPF Marker

The HNRNPF (Human Nuclear Retinol-NP-Fuctor) protein is a protein that is involved in the metabolism of fatty acids and proteins. Its occurrence in the body is associated with aging, obesity, and metabolic diseases. Researchers have found that it is a key player in these conditions. In the context of biomarkers, it is an important marker because of its anti-oxidant and antioxidant properties.

Boster offers high-affinity primary antibodies

If you're searching for high-affinity primary antibodies for your research, consider Boster Bio. Boster Bio produces quality reagents and kits to suit a variety of applications. Their line of antibodies includes WB, Flow, and IHC-optimized polyclonal antibodies. They're validated against panels of 250 human tissues and un-transfected cell lines, resulting in high affinity.

The anti-KHDRBS2 antibody from Boster Bio is a monoclonal antibody tested for use in IHC and WB. This antibody is specific for human and reacts to KHDRBS2 protein. The antibody is supplied in 100 ul liquid form. It has been used to measure the amount of KHDRBS2 protein in a variety of samples, including human cells.

Other quality products from Boster Bio include cDNA clones, protein purification and reagents for ELISA. These products can help you find the right proteins in your experiments. You can also use these antibodies to make diagnostic kits or perform gene expression analysis. They are made by scientists with years of experience in producing antibodies for a wide range of applications. Boster Bio also provides a wide range of antibodies and ELISA kits.

While the discovery of high-affinity antibodies is challenging, the company's process makes it easier for researchers to get the antibodies they need. By developing a proprietary process to produce these antibodies, Boster Bio has significantly shortened the antibody discovery and development timeline. The development of COVID-19 antibodies has been accelerated thanks to its expertise and capabilities. In addition to high affinity antibodies, Boster Bio also offers multiple variants that are optimized for specificity and safety.

These primary and secondary antibodies work together to detect specific antigens in samples. This allows researchers to ask more questions about a specimen, providing a more robust answer and more contextual data. In addition, high-affinity primary antibodies are characterized by low titers of unintended antigens. Ultimately, high-affinity primary antibodies allow researchers to detect, purify, and measure specific antigens.

Agrisera is a Swedish antibody company specializing in monoclonal and polyclonal antibodies. Their primary antibodies are suitable for the detection of plant proteins and are reactive with thousands of plant species. They've won awards for their primary antibodies and have been cited in thousands of scientific articles. The company was recently awarded Plant Science Antibody Supplier of the Year, and its products are available to scientists worldwide.

High-affinity antibodies may be essential for certain applications. In vitro neutralization of ricin is correlated with antibody affinity. However, in animal studies, the potency of the antibodies correlates with neutralization potency. MH2, MH75, and MH76 are highly efficient in neutralizing ricin. While MH49 and MH67 do not fall within this correlation, these antibodies were chosen because they bind the same epitope.

In a recent study, researchers at Boster Bio were able to identify the biological limits of affinity maturation and repertoire diversification. Two adults were vaccinated three consecutive times with tetanus toxoid, and each matured independently after the third vaccination. The third vaccination induced no significant changes in somatic mutations and binding rate constants, suggesting that fully matured Ab repertoires are similar in size, genetically diverse, and dynamic.

Boster offers a fusion protein

The boster bio company offers a HNRNPF fusion-protein that is capable of binding to DHX36 and containing the HNRNPF motif. The boster protein is purified by using conventional chromatography techniques. The boster protein capture is highly efficient and applies to scientists world-wide. The boster HNRNPF fusion-protein is suitable for studies of cell signaling pathways.

The company has successfully produced MBP fusion proteins using variants of the AtCPSF30 gene. The fusion proteins have a central zinc-finger domain responsible for calmodulin binding. The 30M representation shows the nonfunctional calmodulin-binding motif. The fusion proteins that bound RNA are listed under RNA-binding. The binding activity is plotted as a function of protein concentration.