High mobility group protein 20A (HMG20A)

Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B.

Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).