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- Table of Contents
Facts about High mobility group protein 20A.
Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).
Human | |
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Gene Name: | HMG20A |
Uniprot: | Q9NP66 |
Entrez: | 10363 |
Belongs to: |
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No superfamily |
FLJ10739; high-mobility group 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMGX1HMG domain-containing protein HMGX1; HMGXB1high mobility group protein 20A
Mass (kDA):
40.144 kDA
Human | |
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Location: | 15q24.3 |
Sequence: | 15; NC_000015.10 (77420651..77519899) |
Nucleus.
PMID: 10773667 by Sumoy L., et al. HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression.