HLX Antibodies

AND HLX ELISA kits, HLX Proteins

Many biological assays use antibodies to detect HLX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HLX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HLX antibodies...

We validate the specificity of these antibodies to HLX by testing them on tissues known to express HLX positively and negatively. Browse below to find the HLX antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HLX Infographic by Boster Bio

All HLX Products

Product

Figures

Specificity

Applications

Price

Anti-HLX/Hlx11 Antibody

Human, Mouse, Rat

$399
Cat # A06177-1
100μl

Anti-HLX1 Monoclonal Antibody

6 Q&As

Bovine, Human, Mouse, Pig, Rat

$399
Cat # A06177-2
100μl

Anti-HLX/Hlx11 Antibody

1 Q&As

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$335
Cat # A30494
100ul

Anti-HLX1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A06177
100ul

HLX1 (HLX) (NM_021958) Human Over-expression Lysate

Human

$628
Cat # LS003142
100 µg

HLX Overview

Facts about H2.0-like homeobox protein.

HLX 3D structure. Source: alphafold

H2.0-like homeobox protein (HLX)

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as upkeep of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).

. .

Gene Information

Human
Gene Name:	HLX
Uniprot:	Q14774
Entrez:	3142

Family

Belongs to:

H2.0 homeobox family

Alternative Names

H2.0 (Drosophila)-like homeo box 1; H2.0-like homeo box 1; H2.0-like homeo box-1; H2.0-like homeobox 1; H2.0-like homeobox protein; H2.0-like homeobox; HB24; HLX1H2.0-like homeobox 1 (Drosophila); Homeobox protein HB24; Homeobox protein HLX1

Molecular Weight

Mass (kDA):
50.789 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (220879443..220885059)

Tissue Specificity

Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Childhood Asthma
Asthma
Myeloid Leukemia
Fetal Growth Retardation
Neoplasms
Congenital Abnormality
Leukemia, Myelocytic, Acute
Tissue Adhesions
Diaphragmatic Hernia
Disorder Of Pregnancy
Congenital Diaphragmatic Hernia
Hernia

Nervousness
Malignant Neoplasms
Liver Diseases
Immediate Hypersensitivity
Gall Bladder Diseases
Disease Of Adrenal Medulla
Neoplasms, Second Primary

Interacting Proteins

SUZ12

Pathways

Cell Differentiation
Cell Adhesion
Cell Migration
Liver Development
Phagocytosis
Chromatin Remodeling
Diaphragm Development
Cell Proliferation
Endocytosis
Localization
Secretion
Cell Activation
Neutrophil Differentiation

Colony Morphology
T Cell Activation
Interferon-gamma Production
Cytokine Secretion
Inflammatory Response
Cell Maturation
Tissue Development

PTMs

Methylation

Demethylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HLX

References

PMID: 1676597 by Deguchi Y., et al. Cloning of a human homeobox gene that resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes.

PMID: 7806220 by Kennedy M.A., et al. Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1.