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- Table of Contents
Facts about HLA class II histocompatibility antigen, DO alpha chain.
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Human | |
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Gene Name: | HLA-DOA |
Uniprot: | P06340 |
Entrez: | 3111 |
Belongs to: |
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MHC class II family |
HLA class II histocompatibility antigen, DO alpha chain; HLA-D0-alpha; HLA-DNAHLADZ; HLA-DZA; lymphocyte antigen; major histocompatibility complex, class II, DN alpha; major histocompatibility complex, class II, DO alpha; MHC class II antigen DOA; MHC DN-alpha; MHC DZ alpha
Mass (kDA):
27.599 kDA
Human | |
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Location: | 6p21.32 |
Sequence: | 6; NC_000006.12 (33004182..33009591, complement) |
Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
PMID: 3000765 by Trowsdale J., et al. The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions.
PMID: 2499532 by Jonsson A.-K., et al. Human class II DNA and DOB genes display low sequence variability.