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- Table of Contents
Facts about HLA class II histocompatibility antigen, DO beta chain.
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Human | |
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Gene Name: | HLA-DOB |
Uniprot: | P13765 |
Entrez: | 3112 |
Belongs to: |
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MHC class II family |
DOB; FLJ57033; HLA class II histocompatibility antigen, DO beta chain; major histocompatibility complex, class II, DO beta; MHC class II antigen DOB
Mass (kDA):
30.822 kDA
Human | |
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Location: | 6p21.32 |
Sequence: | 6; NC_000006.12 (32812763..32817002, complement) |
Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
PMID: 2998758 by Tonnelle C., et al. DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.
PMID: 2499532 by Jonsson A.-K., et al. Human class II DNA and DOB genes display low sequence variability.