HERPUD1 Antibodies

AND HERPUD1 ELISA kits, HERPUD1 Proteins

Many biological assays use antibodies to detect HERPUD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HERPUD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HERPUD1 antibodies...

We validate the specificity of these antibodies to HERPUD1 by testing them on tissues known to express HERPUD1 positively and negatively. Browse below to find the HERPUD1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HERPUD1 Infographic by Boster Bio

All HERPUD1 Products

Product

Figures

Specificity

Applications

Price

Anti-HERPUD1 Antibody

Human

IHC, WB

$405
Cat # A04908
100ul

HERPUD1 (NM_001010989) Human Recombinant Protein

$1249
Cat # PROTQ15011
20 µg

Anti-HERPUD1 Mouse Monoclonal Antibody [Clone ID: OTI1A2]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04908
100 µl

HERPUD1 (NM_014685) Human Over-expression Lysate

Human

$628
Cat # LS009709
100 µg

Anti-HERP/HERPUD1 Antibody Picoband™

+13

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A04908-2
100 µg/vial

HERPUD1 Overview

Facts about Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein.

HERPUD1 3D structure. Source: alphafold

Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1)

Component of the endoplasmic reticulum quality control (ERQC) system also known as ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation.

Binds to ubiquilins and this interaction is required for efficient degradation of CD3D through the ERAD pathway (PubMed:18307982). .

Gene Information

Human
Gene Name:	HERPUD1
Uniprot:	Q15011
Entrez:	9709

Family

Belongs to:

No superfamily

Alternative Names

HERPMIF1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-likedomain member 1 protein; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-likedomain member 1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domainmember 1 protein; KIAA0025MMS-inducible; Methyl methanesulfonate (MMF)-inducible fragment protein 1; Mif1; SUP

Molecular Weight

Mass (kDA):
43.72 kDA

Genomic Context


Human

Location:	16q13
Sequence:	16; NC_000016.10 (56932142..56944864)

Tissue Specificity

Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Endoplasmic Reticulum Stress
Neoplasms
Carcinoma
Malignant Neoplasms
Hyperhomocysteinemia
Lupus Erythematosus, Systemic
Parkinson Disease
Neoplasm Metastasis
Lupus Nephritis
Nephritis
Physiological Stress
Prostatic Neoplasms

Inflammation
Neurodegenerative Disorders
Neuroblastoma
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Virus Diseases

Pathways

Cell Death
Pathogenesis
Proteolysis
Secretion
Dna Methylation
Methylation
Secretory Pathway
Response To Stress
Dna Hypermethylation
Localization
Protein Unfolding
Spermatogenesis
Demethylation

Flight
Mrna Splicing
Translation
Cell Cycle
Protein Folding
Cell Differentiation
T Cell Receptor Signaling Pathway

PTMs

Ubiquitination
Phosphorylation
Methylation

Demethylation
Glycosylation
Cleavage

Gamma-cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HERPUD1

References

PMID: 10922362 by Kokame K., et al. Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress.

PMID: 11112790 by Kokame K., et al. Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response.