Hephaestin Antibodies

AND HEPH ELISA kits, Hephaestin Proteins

Many biological assays use antibodies to detect Hephaestin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hephaestin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hephaestin antibodies...

We validate the specificity of these antibodies to Hephaestin by testing them on tissues known to express HEPH positively and negatively. Browse below to find the HEPH antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HEPH Infographic by Boster Bio

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Hephaestin (HEPH) (NM_138737) Human Over-expression Lysate

Human

$628
Cat # LS009843
100 µg

HEPH Overview

Facts about Hephaestin.

HEPH 3D structure. Source: alphafold

Hephaestin (HEPH)

May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and might mediate iron efflux associated to ferroportin 1.

Gene Information

Human
Gene Name:	HEPH
Uniprot:	Q9BQS7
Entrez:	9843

Family

Belongs to:

multicopper oxidase family

Alternative Names

EC 1.16.3.1; hephaestin; KIAA0698CPL

Molecular Weight

Mass (kDA):
130.449 kDA

Genomic Context


Human

Location:	Xq12
Sequence:	X; NC_000023.11 (66162526..66268863)

Tissue Specificity

Detected in breast, colon, bone trabecular cells and fibroblasts.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Anemia
Iron Overload
Hemochromatosis
Iron Deficiency
Iron Deficiency Anemia
Hereditary Hemochromatosis
Copper Deficiency
Age Related Macular Degeneration
Iron Metabolism Disorders
Liver Diseases
Hypochromic Anemia
Carcinoma

Hypoxia
Colorectal Cancer
Hyperplasia
Retinal Degeneration
Siderosis
Ceruloplasmin Deficiency
Malignant Neoplasms

Pathways

Transport
Pathogenesis
Localization
Cell Adhesion
Transepithelial Transport
Cellular Localization
Iron Assimilation
Secretory Pathway
Lactation
Parturition
Electron Transport
Immune Response
Glycosylation

Complement Activation
Endocytosis
Intestinal Absorption
Senescence
Reverse Transcription
Cell Cycle
Oxygen Transport

PTMs

Biotinylation

Glycosylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HEPH

References

PMID: 11932491 by Syed B.A., et al. Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin.