ELMO1 Antibodies

AND ELMO1 ELISA kits, ELMO1 Proteins

Many biological assays use antibodies to detect ELMO1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ELMO1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ELMO1 antibodies...

We validate the specificity of these antibodies to ELMO1 by testing them on tissues known to express ELMO1 positively and negatively. Browse below to find the ELMO1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELMO1 Infographic by Boster Bio

All ELMO1 Products

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Product

Figures

Specificity

Applications

Price

Anti-ELMO1 Antibody

Human, Mouse, Rat

$405
Cat # A03091
100ul

Anti-ELMO1 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IHC, WB

$405
Cat # A03091-1
100ul

ELMO1 (NM_014800) Human Recombinant Protein

$1249
Cat # PROTQ92556
20 µg

Anti-ELMO1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M03091-1
100 μl/vial

ELMO1 (NM_014800) Human Over-expression Lysate

Human

$960
Cat # LS009844
100 µg

ELMO1 Overview

Facts about Engulfment and cell motility protein 1.

ELMO1 3D structure. Source: alphafold

Engulfment and cell motility protein 1 (ELMO1)

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK.

Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May improve the guanine nucleotide exchange factor (GEF) activity of DOCK1.

Gene Information

Human
Gene Name:	ELMO1
Uniprot:	Q92556
Entrez:	9844

Family

Belongs to:

No superfamily

Alternative Names

ced-12 homolog 1; CED12CED-12; ELMO-1; engulfment and cell motility 1 (ced-12 homolog, C. elegans); engulfment and cell motility 1; engulfment and cell motility protein 1; KIAA0281MGC126406; Protein ced-12 homolog

Molecular Weight

Mass (kDA):
83.829 kDA

Genomic Context


Human

Location:	7p14.2-p14.1
Sequence:	7; NC_000007.14 (36852906..37449326, complement)

Tissue Specificity

Widely expressed, with a higher expression in the spleen and placenta.

Subcellular Localizations

Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.

Diseases

Diabetic Nephropathy
Kidney Diseases
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Kidney Failure, Chronic
Cell Invasion
Malignant Neoplasms
Neoplasms
Tissue Adhesions
Neoplasm Metastasis
Tumor Angiogenesis
Diabetes Mellitus, Insulin-dependent
Hiv Infections

Autoimmunity
Chronic Kidney Disease
Retinal Diseases
Renal Glomerular Disease
Trematode Infections
Malignant Paraganglionic Neoplasm
Complications Of Diabetes Mellitus

Interacting Proteins

ADGRB1
Adgrb1
DOCK1
HCK
RHOG

TRIM54
ZNF398

Pathways

Cell Migration
Cell Motility
Phagocytosis
Localization
Cell Adhesion
Chemotaxis
Pathogenesis
Cytokinesis
Lymphocyte Migration
Angiogenesis
Spermatogenesis
Lymphocyte Chemotaxis
Myoblast Fusion

Actin Cytoskeleton Reorganization
Rna Interference
Tissue Homeostasis
Apoptotic Cell Clearance
Cell Activation
Response To Wounding
Cellular Homeostasis

PTMs

Phosphorylation

Ribosylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELMO1

References

PMID: 11595183 by Gumienny T.L., et al. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

PMID: 9179496 by Ohara O., et al. Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.