HECTD1 Antibodies

AND HECTD1 ELISA kits, HECTD1 Proteins

Many biological assays use antibodies to detect HECTD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HECTD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HECTD1 antibodies...

We validate the specificity of these antibodies to HECTD1 by testing them on tissues known to express HECTD1 positively and negatively. Browse below to find the HECTD1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HECTD1 Infographic by Boster Bio

All HECTD1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HECTD1 Antibody

Human

$405
Cat # A08428
100ul

Anti-HECD1 HECTD1 Antibody

Human, Mouse

IHC

$380
Cat # A08428-1
100ul

Anti-HECTD1 Antibody Picoband®

Human

ELISA, IHC, WB

$370
Cat # A08428-2
100 μg/vial

HECTD1 Overview

Facts about E3 ubiquitin-protein ligase HECTD1.

HECTD1 3D structure. Source: alphafold

E3 ubiquitin-protein ligase HECTD1 (HECTD1)

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates'Lys-63'-linked polyubiquitination of HSP90AA1 which contributes to its intracellular localization and decreased secretion.

Negatively controlling HSP90AA1 secretion in cranial mesenchyme cells can impair their emigration and could be essential for the correct development of the cranial neural folds and neural tube closure. .

Gene Information

Human
Gene Name:	HECTD1
Uniprot:	Q9ULT8
Entrez:	25831

Family

Belongs to:

UPL family

Alternative Names

E3 ligase for inhibin receptor; E3 ubiquitin-protein ligase HECTD1; EC 6.3.2.-; EULIR; HECT domain containing 1; HECT domain-containing protein 1; KIAA1131FLJ38315

Molecular Weight

Mass (kDA):
289.384 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (31100117..31207793, complement)

Diseases

Exencephaly
Abnormal Behavior
Crest Syndrome

Pathways

Tube Closure
Neural Tube Closure
Mesenchyme Development
Localization
Secretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HECTD1

References

PMID: 12421765 by Nakayama M., et al. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.