Orexin receptor type 1 Antibodies

AND HCRTR1 ELISA kits, Orexin receptor type 1 Proteins

Many biological assays use antibodies to detect Orexin receptor type 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Orexin receptor type 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Orexin receptor type 1 antibodies...

We validate the specificity of these antibodies to Orexin receptor type 1 by testing them on tissues known to express HCRTR1 positively and negatively. Browse below to find the HCRTR1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HCRTR1 Overview

Facts about Orexin receptor type 1.

Orexin receptor type 1 (HCRTR1)

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Gene Information

Human
Gene Name:	HCRTR1
Uniprot:	O43613
Entrez:	3061

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

HCRTR1; hypocretin (orexin) receptor 1; hypocretin receptor 1; Hypocretin receptor type 1; hypocretin receptor-1; Orexin R1; orexin receptor 1; orexin receptor type 1; orexin receptor-1; OrexinR1; OX1R; ox-1-R; ox1-R

Molecular Weight

Mass (kDA):
47.536 kDA

Genomic Context


Human

Location:	1p35.2
Sequence:	1; NC_000001.11 (31617689..31632518)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Narcolepsy
Sleep Disorders
Depressive Disorder
Excessive Daytime Somnolence
Cataplexy
Psychogenic Polydipsia
Polydipsia
Anxiety Disorders
Schizophrenia
Disease Of Adrenal Medulla
Feeling Despair
Mood Disorders
Sarcoma

Common Migraine
Nervousness
Myotonic Dystrophy
Disorders Of Excessive Somnolence
Dysequilibrium Syndrome
Gliosis
Primary Hypersomnia

Interacting Proteins

LEPR

Pathways

Drinking Behavior
Pathogenesis
Localization

PTMs

Disulfide bond

Glycoprotein

Research Areas

Cancer
GPCR
Neuronal Cell Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HCRTR1

References

PMID: 9491897 by Sakurai T., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

PMID: 10973318 by Peyron C., et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.