Orexin receptor type 2 Antibodies

AND HCRTR2 ELISA kits, Orexin receptor type 2 Proteins

Many biological assays use antibodies to detect Orexin receptor type 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Orexin receptor type 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Orexin receptor type 2 antibodies...

We validate the specificity of these antibodies to Orexin receptor type 2 by testing them on tissues known to express HCRTR2 positively and negatively. Browse below to find the HCRTR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HCRTR2 Infographic by Boster Bio

All HCRTR2 Products

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Product

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Specificity

Applications

Price

Anti-OX2R HCRTR2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04037
100ul

Orexin Receptor 2 (HCRTR2) (NM_001526) Human Over-expression Lysate

Human

$960
Cat # LS003062
100 µg

HCRTR2 Overview

Facts about Orexin receptor type 2.

HCRTR2 3D structure. Source: alphafold

Orexin receptor type 2 (HCRTR2)

Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).

Gene Information

Human
Gene Name:	HCRTR2
Uniprot:	O43614
Entrez:	3062

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

HCRTR2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2; Orexin R2; Orexin Receptor 2; orexin receptor type 2; OrexinR2; OX2R; Ox-2-R; ox2-R

Molecular Weight

Mass (kDA):
50.694 kDA

Genomic Context


Human

Location:	6p12.1
Sequence:	6; NC_000006.12 (55106460..55284698)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Narcolepsy
Headache
Cluster Headache
Cataplexy
Sleep Disorders
Excessive Daytime Somnolence
Primary Hypersomnia
Depressive Disorder
Dog Diseases
Pain
Headache Disorders
Anxiety Disorders
Nervousness

Migraine Disorders
Disease Of Adrenal Medulla
Feeling Despair
Infectious Mononucleosis
Migraine With Aura
Benign Prostatic Hypertrophy
Sarcoma

Pathways

Pathogenesis
Localization
Reverse Transcription
Drinking Behavior
Immune Response
Energy Homeostasis

PTMs

Ubiquitination

Research Areas

Adaptive Immunity
GPCR
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HCRTR2

References

PMID: 9491897 by Sakurai T., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

PMID: 11723285 by Olafsdottir B.R., et al. Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.