Host cell factor 1 Antibodies

AND HCFC1 ELISA kits, Host cell factor 1 Proteins

Many biological assays use antibodies to detect Host cell factor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Host cell factor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Host cell factor 1 antibodies...

We validate the specificity of these antibodies to Host cell factor 1 by testing them on tissues known to express HCFC1 positively and negatively. Browse below to find the HCFC1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HCFC1 Infographic by Boster Bio

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Anti-HCFC1/Hcf1 Antibody

5 Q&As

Human, Mouse

IHC

$360
Cat # A01729
100 µl

HCFC1 Overview

Facts about Host cell factor 1.

HCFC1 3D structure. Source: alphafold

Host cell factor 1 (HCFC1)

Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655).
Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100).

Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868).

Gene Information

Human
Gene Name:	HCFC1
Uniprot:	P51610
Entrez:	3054

Family

Belongs to:

No superfamily

Alternative Names

C1 Factor; CFF; CFFC1 factor; HCF; HCF1; HCF1HFC1; HCF-1VP16 accessory protein; HCFC1; HFC1; host cell factor C1 (VP16-accessory protein); MGC70925; VCAFhost cell factor 1

Molecular Weight

Mass (kDA):
208.732 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (153947556..153972360, complement)

Tissue Specificity

Highly expressed in fetal tissues and the adult kidney. Present in all tissues tested.

Subcellular Localizations

Cytoplasm. Nucleus. HCFC1R1 modulates its subcellular localization and overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm (PubMed:12235138). Non-processed HCFC1 associates with chromatin. Colocalizes with CREB3 and CANX in the ER.