HCAR1 Antibodies

AND HCAR1 ELISA kits, HCAR1 Proteins

Many biological assays use antibodies to detect HCAR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HCAR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HCAR1 antibodies...

We validate the specificity of these antibodies to HCAR1 by testing them on tissues known to express HCAR1 positively and negatively. Browse below to find the HCAR1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HCAR1 Infographic by Boster Bio

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Anti-GPR81 HCAR1 Antibody

Human, Mouse, Rat

$405
Cat # A08237
100ul

HCAR1 Overview

Facts about Hydroxycarboxylic acid receptor 1.

HCAR1 3D structure. Source: alphafold

Hydroxycarboxylic acid receptor 1 (HCAR1)

Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. .

Gene Information

Human
Gene Name:	HCAR1
Uniprot:	Q9BXC0
Entrez:	27198

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

FKSG80; G protein-coupled receptor 104; G protein-coupled receptor 81; GPR104; GPR81; G-protein coupled receptor 104; G-protein coupled receptor 81; HCA1; HCAR1; LACR1; lactate receptor 1; TA-GPCR; T-cell activation G protein-coupled receptor

Molecular Weight

Mass (kDA):
39.295 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (122726076..122730844, complement)

Tissue Specificity

Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Pathways

Transport
Localization

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HCAR1

References

PMID: 11574155 by Lee D.K., et al. Discovery and mapping of ten novel G protein-coupled receptor genes.

PMID: 19047060 by Liu C., et al. Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.