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Histone H1.4 Antibodies

AND H1-4 ELISA kits, Histone H1.4 Proteins

Many biological assays use antibodies to detect Histone H1.4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H1.4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H1.4 antibodies...

We validate the specificity of these antibodies to Histone H1.4 by testing them on tissues known to express H1-4 positively and negatively. Browse below to find the H1-4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H1-4 Infographic by Boster Bio

H1-4 protein infographic

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Histone H1.4 (HIST1H1E) (NM_005321) Human Over-expression Lysate

Human

$628
Cat # LS003008
100 µg

H1-4 Overview

Facts about Histone H1.4.

H1-4 3D structure

H1-4 3D structure. Source: alphafold

Histone H1.4 (H1-4)

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.

Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .

Gene Information

Human
Gene Name:	H1-4
Uniprot:	P10412
Entrez:	3008

Gene Information

Family

Belongs to:

histone H1/H5 family

Family

Alternative Names

Histone H1.4

Molecular Weight

Mass (kDA):
21.865 kDA

Molecular Weight

Genomic Context


Human

Location:	6p22.2
Sequence:	6; NC_000006.12 (26156329..26157115)

Subcellular Localizations

Nucleus. Chromosome. Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.

Subcellular Localization

Diseases

Rahman syndrome (RMNS)

Disease

Interacting Proteins

FTSJ3
L3MBTL1
NCK1

Interacting Proteins

PTMs

Acetylation
ADP-ribosylation
Citrullination

Hydroxylation
Methylation
Phosphoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H1-4

References

PMID: 1916825 by Albig W., et al. Isolation and characterization of two human H1 histone genes within clusters of core histone genes.

PMID: 3782055 by Ohe Y., et al. Human spleen histone H1. Isolation and amino acid sequence of a main variant, H1b.