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- Table of Contents
Facts about G-protein coupled receptor family C group 6 member A.
Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(I)-coupled pathway.
Mouse | |
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Gene Name: | Gprc6a |
Uniprot: | Q8K4Z6 |
Entrez: | 210198 |
Belongs to: |
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G-protein coupled receptor 3 family |
bA86F4.3; G protein-coupled receptor, family C, group 6, member A; GPCR; GPCR33; GPRC6A; G-protein coupled receptor family C group 6 member A; G-protein coupled receptor GPCR33; hGPCR33; hGPRC6A; predicted with SOSUI analysis; seven transmembrane helix receptor
Mass (kDA):
104.213 kDA
Mouse | |
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Location: | 10|10 B3 |
Sequence: | 10; |
Expressed at high level in liver, lung, spleen and heart. Expressed at lower level in kidney, skeletal muscle and brain. Expressed in E7, E11, E15 and E17 embryos.
PMID: 15816861 by Kuang D., et al. Cloning and characterization of a family C orphan G-protein coupled receptor.
PMID: 15576628 by Wellendorph P., et al. Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.