G-protein coupled receptor family C group 6 member A (Gprc6a)

Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is reinforced by divalent cations Ca(2+) and Mg(2+).

Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(I)-coupled pathway.