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- Table of Contents
Facts about Integral membrane protein GPR137B.
Human | |
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Gene Name: | GPR137B |
Uniprot: | O60478 |
Entrez: | 7107 |
Belongs to: |
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GPR137 family |
G protein-coupled receptor 137B; TM7SF1; transmembrane 7 superfamily member 1 (upregulated in kidney)
Mass (kDA):
45.599 kDA
Human | |
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Location: | 1q42.3 |
Sequence: | 1; NC_000001.11 (236142529..236213535) |
Expressed in kidney, heart, brain and placenta.
Lysosome membrane; Multi-pass membrane protein. Colocalized with MTOR in lysosome after amino acid stimulation.
PMID: 9521871 by Spangenberg C., et al. Cloning and characterization of a novel gene (TM7SF1) encoding a putative seven-pass transmembrane protein that is upregulated during kidney development.
PMID: 22729905 by Gao J., et al. TM7SF1 (GPR137B): a novel lysosome integral membrane protein.