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- Table of Contents
Facts about Glioma pathogenesis-related protein 1.
Human | |
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Gene Name: | GLIPR1 |
Uniprot: | P48060 |
Entrez: | 11010 |
Belongs to: |
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CRISP family |
GLI pathogenesis-related 1 (glioma); GLI pathogenesis-related 1; GliPR 1; GliPR; GLIPR1; GLIPRglioma pathogenesis-related protein 1; Protein RTVP-1; related to testis-specific, vespid, and pathogenesis proteins 1; RTVP1; RTVP-1; RTVP1CRISP7; testes-specific vespid and pathogenesis protein 1
Mass (kDA):
30.366 kDA
Human | |
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Location: | 12q21.2 |
Sequence: | 12; NC_000012.12 (75480754..75503863) |
According to PubMed:8973356, it is ubiquitously expressed with high levels in lung and kidney and low levels in heart and liver. Highly expressed in cell lines derived from nervous system tumors arising from glia, low or absent in non-glial-derived nervous system tumor cell lines. Also found in fetal kidney. According to PubMed:7607567 it is expressed only in brain tumor glioblastoma multiforme/astrocytoma and not in other nervous system tumors or normal fetal or adult tissues.
Membrane; Single-pass membrane protein.
PMID: 7607567 by Murphy E.V., et al. The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors.
PMID: 8973356 by Rich T., et al. RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial but not neuronal origin.