Gliomedin Antibodies

AND Gldn ELISA kits, Gliomedin Proteins

Many biological assays use antibodies to detect Gliomedin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gliomedin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gliomedin antibodies...

We validate the specificity of these antibodies to Gliomedin by testing them on tissues known to express Gldn positively and negatively. Browse below to find the Gldn antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Gldn Overview

Facts about Gliomedin.

Gliomedin (Gldn)

Ligand for NRCAM and NFASC/neurofascin that plays a part in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC (PubMed:20188654).

Nodes of Ranvier contain clustered sodium channels which are crucial for the saltatory propagation of action potentials along myelinated axons. During growth, nodes of Ranvier are formed by the fusion of two heminodes.

Gene Information

Mouse
Gene Name:	Gldn
Uniprot:	Q8BMF8
Entrez:	235379

Family

Belongs to:

No superfamily

Alternative Names

CLOM; collomin; COLM; colmedin; CRGL2; CRG-L2; FLJ23917; gliomedin; UNC-112

Molecular Weight

Mass (kDA):
59.137 kDA

Genomic Context


Mouse

Location:	9\|9 A5.3
Sequence:	9;

Tissue Specificity

Detected in sciatic nerve (at protein level) (PubMed:17293346, PubMed:20188654, PubMed:24719088). Widely expressed with higher expression in testis and skeletal muscle (PubMed:12642876).

Diseases

Nervousness
Gynecomastia
Tissue Adhesions

Pathways

Cell Adhesion
Translation
Clustering Of Voltage-gated Sodium Channels

PTMs

Glycoprotein

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gldn

References

PMID: 12642876 by Graveel C.R., et al. Identification and characterization of CRG-L2, a new marker for liver tumor development.

PMID: 16039564 by Eshed Y., et al. Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier.