GIMAP5 Antibodies

AND GIMAP5 ELISA kits, GIMAP5 Proteins

Many biological assays use antibodies to detect GIMAP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GIMAP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GIMAP5 antibodies...

We validate the specificity of these antibodies to GIMAP5 by testing them on tissues known to express GIMAP5 positively and negatively. Browse below to find the GIMAP5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GIMAP5 Infographic by Boster Bio

All GIMAP5 Products

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Product

Figures

Specificity

Applications

Price

Anti-GTPase IMAP family member 5 GIMAP5 Antibody

3 Q&As

Human

IHC, WB

$360
Cat # A07653
100 µl

Anti-GIMAP5 Antibody

1 Q&As

Human, Mouse, Rat

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A30712
100ul

GIMAP5 (NM_018384) Human Recombinant Protein

$1249
Cat # PROTQ96F15
20 µg

GIMAP5 (NM_018384) Human Over-expression Lysate

Human

$628
Cat # LS055340
100 µg

GIMAP5 Overview

Facts about GTPase IMAP family member 5.

GIMAP5 3D structure. Source: alphafold

GTPase IMAP family member 5 (GIMAP5)

Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity).

. .

Gene Information

Human
Gene Name:	GIMAP5
Uniprot:	Q96F15
Entrez:	55340

Family

Belongs to:

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

Alternative Names

FLJ11296; GTPase, IMAP family member 5; hIAN5; HIMAP3; IAN4; IAN4L1IROD; IAN5; IAN-5; IMAP3GTPase IMAP family member 5; immune associated nucleotide 4 like 1 (mouse); immune associated nucleotide 4 like 1; immunity associated protein 3; Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; Immunity-associated protein 3; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5

Molecular Weight

Mass (kDA):
34.846 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (150737348..150743649)

Tissue Specificity

Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T- cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms.

Subcellular Localizations

Lysosome membrane; Single-pass type IV membrane protein. Endosome, multivesicular body membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein. The mitochondrial localization originally reported was observed with C-terminally tagged protein and was not confirmed in later publications.

Diseases

Lymphopenia
Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Autoimmune Reaction
Lymphomatoid Papulosis
Autoimmune Diseases
Autoimmunity
Diabetes Mellitus, Experimental
Hyperglycemia
Leukemia
Immunologic Tolerance
Lupus Erythematosus, Systemic
Colitis

Diabetes, Autoimmune
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Inflammation
Liver Diseases
Leukemia, T-cell
Inflammatory Bowel Diseases
Intestinal Diseases

Interacting Proteins

EDA
GRAMD2B
LDLRAD1
LSMEM2
STX4

Pathways

Localization
Cell Development
Pathogenesis
Cell Death
Methylation
Lipid Oxidation
T Cell Homeostasis
Lymphocyte Homeostasis

Rna Interference
Cell Maturation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GIMAP5

References

PMID: 14724691 by Zenz T., et al. hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies.

PMID: 16509771 by Nitta T., et al. IAN family critically regulates survival and development of T lymphocytes.