Gdf6 Antibodies

AND Gdf6 ELISA kits, Gdf6 Proteins

Many biological assays use antibodies to detect Gdf6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gdf6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gdf6 antibodies...

We validate the specificity of these antibodies to Gdf6 by testing them on tissues known to express Gdf6 positively and negatively. Browse below to find the Gdf6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Gdf6 Infographic by Boster Bio

All Gdf6 Products

Product

Figures

Specificity

Applications

Price

Anti-GDF-6 Antibody

4 Q&As

Human, Mouse, Rat

$399
Cat # A05536
100μl

BMP13 Bone Morphogenetic protein-13 Human Recombinant Protein

Human

$250
Cat # PROTQ6KF10
10ug, 50ug, 1mg

Gdf6 Overview

Facts about Growth/differentiation factor 6.

Growth/differentiation factor 6 (Gdf6)

Growth factor that regulates proliferation and cellular differentiation in the retina and bone formation. Plays a crucial role in regulating apoptosis during retinal development.

Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map (PubMed:23307924). Plays a crucial role in establishing boundaries between skeletal elements during development.

Gene Information

Mouse
Gene Name:	Gdf6
Uniprot:	P43028
Entrez:	242316

Family

Belongs to:

TGF-beta family

Alternative Names

BMP13; BMP-13; CDMP2; GDF16; GDF6; GDF-6; growth differentiation factor 6; Growth/differentiation factor 16; growth/differentiation factor 6; KFS; KFS1; KFSL; MCOP4; MCOPCB6; MGC158100; MGC158101; SCDO4; SGM1

Molecular Weight

Mass (kDA):
50.942 kDA

Genomic Context


Mouse

Location:	4\|4 A1
Sequence:	4;

Tissue Specificity

Expressed in different subsets of developing joints.

Diseases

Microphthalmos
Anophthalmos
Congenital Ocular Coloboma (disorder)
Klippel-feil Syndrome
Eye Abnormalities
Scoliosis, Unspecified
Cicatrix
Crest Syndrome
Limb Deformities, Congenital
Ectrodactyly
Conductive Hearing Loss
Mirror Movements Disorder
Fundus Coloboma

Congenital Anomaly Of Face
Dysplasia
Hematoma
Tumor Angiogenesis
Hemorrhage
Craniosynostosis
Neoplasms

Pathways

Eye Development
Regeneration
Ossification
Cell Differentiation
Segmentation
Cell Adhesion
Endochondral Ossification
Programmed Cell Death
Neurogenesis
Cell Fate Determination
Pigmentation

Tissue Regeneration
Tendon Formation
Cell Cycle
Cell Death
Regulation Of Angiogenesis
Angiogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gdf6

References

PMID: 8145850 by Storm E.E., et al. Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.

PMID: 12606286 by Settle S.H. Jr., et al. Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes.