GDF2 Antibodies

AND GDF2 ELISA kits, GDF2 Proteins

Many biological assays use antibodies to detect GDF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDF2 antibodies...

We validate the specificity of these antibodies to GDF2 by testing them on tissues known to express GDF2 positively and negatively. Browse below to find the GDF2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GDF2 Infographic by Boster Bio

All GDF2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-BMP-9 GDF2 Antibody

6 Q&As

Human, Mouse

ELISA, IHC

$399
Cat # A03443-1
100μl

Mouse BMP-9 ELISA Kit PicoKine®

8 Q&As

Mouse

ELISA

$499
Cat # EK1610
96 wells/kit, with removable strips.

Rat BMP-9 ELISA Kit PicoKine®

6 Q&As

Rat

ELISA

$499
Cat # EK1611
96 wells/kit, with removable strips.

Human BMP-9 ELISA Kit PicoKine®

9 Q&As

Human

ELISA

$499
Cat # EK1560
96 wells/kit, with removable strips.

Human BMP-9 PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK1560
96 wells/kit, with removable strips.

BMP9 (GDF2) (NM_016204) Human Over-expression Lysate

Human

$628
Cat # LS002658
100 µg

Human recombinant BMP-9 (Bone morphogenetic protein-9) protein, AF

Human

Cell Culture

$77
Cat # PROTQ9UK05-1
5ug,20ug,100ug,500ug,1mg

GDF2 Overview

Facts about Growth/differentiation factor 2.

GDF2 3D structure. Source: alphafold

Growth/differentiation factor 2 (GDF2)

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks.

Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. .

Gene Information

Human
Gene Name:	GDF2
Uniprot:	Q9UK05
Entrez:	2658

Family

Belongs to:

TGF-beta family

Alternative Names

BMP9; BMP-9; BMP9BMP-9Bone morphogenetic protein 9; GDF2; GDF-2; growth differentiation factor 2; growth/differentiation factor 2

Molecular Weight

Mass (kDA):
47.32 kDA

Genomic Context


Human

Location:	10q11.22
Sequence:	10; NC_000010.11 (47322454..47327588)

Tissue Specificity

Detected in blood plasma (at protein level).

Subcellular Localizations

Secreted.

Diseases

Tumor Angiogenesis
Neoplasms
Hereditary Hemorrhagic Telangiectasia
Telangiectasis
Malignant Neoplasms
Pathologic Neovascularization
Tissue Adhesions
Neoplasm Metastasis
Dysplasia
Bone Diseases
Cytomegalovirus Infections
Metastatic Malignant Neoplasm To The Bone

Heterotopic Ossification
Diabetes Mellitus
Nervousness
Cell Invasion
Iron Overload
Cholangiocarcinoma
Malignant Neoplasm Of Breast

Pathways

Angiogenesis
Regeneration
Cell Proliferation
Cell Migration
Osteoblast Differentiation
Ossification
Bmp Signaling Pathway
Tissue Regeneration
Immune Response
Cell Differentiation
Endothelial Cell Migration
Regulation Of Angiogenesis
Pathogenesis

Secretion
Gene Silencing
Tube Formation
Endothelial Cell Proliferation
Glucose Homeostasis
Translation
Bioluminescence

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDF2

References

PMID: 18309101 by David L., et al. Bone morphogenetic protein-9 is a circulating vascular quiescence factor.

PMID: 21737454 by Castonguay R., et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.