GTF3C4 Antibodies

AND GTF3C4 ELISA kits, GTF3C4 Proteins

Many biological assays use antibodies to detect GTF3C4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTF3C4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTF3C4 antibodies...

We validate the specificity of these antibodies to GTF3C4 by testing them on tissues known to express GTF3C4 positively and negatively. Browse below to find the GTF3C4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GTF3C4 Infographic by Boster Bio

All GTF3C4 Products

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Specificity

Applications

Price

Anti-GTF3C4 Antibody

Human, Rat

IF, IHC, ICC, WB

$405
Cat # A12724
100ul

Anti-GTF3C4 Mouse Monoclonal Antibody [Clone ID: OTI4A1]

Human, Monkey, Mouse, Rat

IHC, WB

$523
Cat # M12724
100 µl

GTF3C4 Overview

Facts about General transcription factor 3C polypeptide 4.

GTF3C4 3D structure. Source: alphafold

General transcription factor 3C polypeptide 4 (GTF3C4)

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, such as 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both viral and cellular origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3.

May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized near the A box.

Gene Information

Human
Gene Name:	GTF3C4
Uniprot:	Q9UKN8
Entrez:	9329

Family

Belongs to:

TFIIIC subunit 4 family

Alternative Names

EC 2.3.1.48; FLJ21002; general transcription factor 3C 4; general transcription factor 3C polypeptide 4; general transcription factor IIIC, polypeptide 4 (90kD); general transcription factor IIIC, polypeptide 4, 90kDa; KAT12; TF3C-delta; TFIII90; TFIIIC 90 kDa subunit; TFIIIC290; TFIIIC90MGC138450; TFIIICDELTA; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta

Molecular Weight

Mass (kDA):
91.982 kDA

Genomic Context


Human

Location:	9q34.13
Sequence:	9; NC_000009.12 (132670035..132694955)

Subcellular Localizations

Nucleus.

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GTF3C4

References

PMID: 10523658 by Hsieh Y.-J., et al. The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.

PMID: 17409385 by Dumay-Odelot H., et al. Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.