GTF3C1 Antibodies

AND GTF3C1 ELISA kits, GTF3C1 Proteins

Many biological assays use antibodies to detect GTF3C1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTF3C1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTF3C1 antibodies...

We validate the specificity of these antibodies to GTF3C1 by testing them on tissues known to express GTF3C1 positively and negatively. Browse below to find the GTF3C1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GTF3C1 Infographic by Boster Bio

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GTF3C1 (NM_001520) Human Over-expression Lysate

Human

$960
Cat # LS002975
100 µg

GTF3C1 Overview

Facts about General transcription factor 3C polypeptide 1.

GTF3C1 3D structure. Source: alphafold

General transcription factor 3C polypeptide 1 (GTF3C1)

Required for RNA polymerase III-mediated transcription.
Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs.

Binds to the box B promoter element. .

Gene Information

Human
Gene Name:	GTF3C1
Uniprot:	Q12789
Entrez:	2975

Family

Belongs to:

TFIIIC subunit 1 family

Alternative Names

general transcription factor 3C polypeptide 1; general transcription factor IIIC, polypeptide 1 (alpha subunit); general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); general transcription factor IIIC, polypeptide 1, alpha 220kDa; TF3C-alpha; TFIIIC 220 kDa subunit; TFIIIC box B-binding subunit; TFIIIC; TFIIIC220DKFZp686A111; TFIIICalpha; Transcription factor IIIC 220 kDa subunit; Transcription factor IIIC subunit alpha

Molecular Weight

Mass (kDA):
238.875 kDA

Genomic Context


Human

Location:	16p12.1
Sequence:	16; NC_000016.10 (27460613..27549922, complement)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Chromosome Break
Mammary Neoplasms

Interacting Proteins

AGTRAP
CMTM5

Pathways

Cell Cycle

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GTF3C1

References

PMID: 8127861 by L'Etoile N.D., et al. Human transcription factor IIIC box B binding subunit.

PMID: 8164661 by Lagna G., et al. Cloning and characterization of an evolutionarily divergent DNA- binding subunit of mammalian TFIIIC.