Gspt2 Antibodies

AND Gspt2 ELISA kits, Gspt2 Proteins

Many biological assays use antibodies to detect Gspt2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gspt2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gspt2 antibodies...

We validate the specificity of these antibodies to Gspt2 by testing them on tissues known to express Gspt2 positively and negatively. Browse below to find the Gspt2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Gspt2 Infographic by Boster Bio

All Gspt2 Products

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Product

Figures

Specificity

Applications

Price

Anti-GSPT2 Mouse Monoclonal Antibody [Clone ID: OTI2G9]

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M09757
100 µl

GSPT2 (NM_018094) Human Over-expression Lysate

Human

$628
Cat # LS023708
100 µg

Gspt2 Overview

Facts about Eukaryotic peptide chain release factor GTP-binding subunit ERF3B.

Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Gspt2)

Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a powerful stimulator of the release factor activity of ETF1.

Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression.

Gene Information

Mouse
Gene Name:	Gspt2
Uniprot:	Q149F3
Entrez:	14853

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

eRF3b; ERF3BGST2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Eukaryotic peptide chain release factor subunit 3b; FLJ10441; G1 to S phase transition 2; G1 to S phase transition protein 2 homolog

Molecular Weight

Mass (kDA):
69.147 kDA

Genomic Context


Mouse

Location:	X\|X C3
Sequence:	X;

Tissue Specificity

Highly expressed in brain. Moderately expressed in spleen and lung. Weakly expressed in heart, liver and kidney. Expression during the cell-cycle progression is constant.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Neoplasms
Colorectal Cancer
Cell Transformation, Neoplastic
Epithelioma
Malignant Neoplasm Of Breast
Learning Disabilities
Neurotoxicity Syndromes
Carcinogenesis
Animal Mammary Neoplasms

Paroxysmal Nocturnal Dyspnea
Maternal Exposure
Nervousness
Chromosome Breakage
Malignant Neoplasm Of Ovary
Mammary Neoplasms

Pathways

Methylation
Cell Proliferation
Translation
Dna Methylation
Cell Cycle
S Phase

PTMs

Methylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gspt2

References

PMID: 9712840 by Hoshino S., et al. Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.

PMID: 12354098 by Le Goff C., et al. Mouse GSPT2, but not GSPT1, can substitute for yeast eRF3 in vivo.