GRXCR1 Antibodies

AND GRXCR1 ELISA kits, GRXCR1 Proteins

Many biological assays use antibodies to detect GRXCR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRXCR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRXCR1 antibodies...

We validate the specificity of these antibodies to GRXCR1 by testing them on tissues known to express GRXCR1 positively and negatively. Browse below to find the GRXCR1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRXCR1 Infographic by Boster Bio

All GRXCR1 Products

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GRXCR1 (NM_001080476) Human Over-expression Lysate

Human

$628
Cat # LS389207
100 µg

GRXCR1 Overview

Facts about Glutaredoxin domain-containing cysteine-rich protein 1.

GRXCR1 3D structure. Source: alphafold

Glutaredoxin domain-containing cysteine-rich protein 1 (GRXCR1)

May play a role in actin filament structure in creating stereocilia of sensory cells. .

Gene Information

Human
Gene Name:	GRXCR1
Uniprot:	A8MXD5
Entrez:	389207

Family

Belongs to:

GRXCR1 family

Alternative Names

DFNB25; glutaredoxin domain-containing cysteine-rich protein 1; glutaredoxin, cysteine rich 1

Molecular Weight

Mass (kDA):
32.294 kDA

Genomic Context


Human

Location:	4p13
Sequence:	4; NC_000004.12 (42893266..43030658)

Tissue Specificity

Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea.

Subcellular Localizations

Cell projection, stereocilium. Cell projection, microvillus. Cell projection, kinocilium. In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia.

Diseases

Circling Gait
Nodular Sclerosis Classical Hodgkin Lymphoma
Complete Hearing Loss
Chromosomal Translocation

Pathways

Localization
Light Absorption

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRXCR1

References

PMID: 20137778 by Schraders M., et al. Homozygosity mapping reveals mutations of GRXCR1 as a cause of autosomal-recessive nonsyndromic hearing impairment.

PMID: 20137774 by Odeh H., et al. Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse.