GRIK3 Antibodies

AND GRIK3 ELISA kits, GRIK3 Proteins

Many biological assays use antibodies to detect GRIK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRIK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRIK3 antibodies...

We validate the specificity of these antibodies to GRIK3 by testing them on tissues known to express GRIK3 positively and negatively. Browse below to find the GRIK3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRIK3 Infographic by Boster Bio

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Anti-Grik3 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A06927
0.1 mg

GRIK3 Overview

Facts about Glutamate receptor ionotropic, kainate 3.

GRIK3 3D structure. Source: alphafold

Glutamate receptor ionotropic, kainate 3 (GRIK3)

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

The postsynaptic actions of Glu are mediated by a number of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.

Gene Information

Human
Gene Name:	GRIK3
Uniprot:	Q13003
Entrez:	2899

Family

Belongs to:

glutamate-gated ion channel (TC 1.A.10.1) family

Alternative Names

EAA5; Excitatory amino acid receptor 5; GLR7; GluK3; GluR7; gluR-7; GluR7a; GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); Glutamate receptor 7; glutamate receptor, ionotropic kainate 3; glutamate receptor, ionotropic, kainate 3; GRIK3

Molecular Weight

Mass (kDA):
104.037 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (36795527..37034515, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Diseases

Schizophrenia
Dysequilibrium Syndrome
Psychotic Disorders
Depressive Disorder
Delirium
Bipolar Disorder
Major Depressive Disorder
Mood Disorders
Personality Disorders

Behavioral Symptoms
Antisocial Personality Disorder
Osteochondritis Dissecans
Delusions

Pathways

Pathogenesis

PTMs

Disulfide bond
Glycoprotein

Isopeptide bond
Phosphoprotein

Ubl conjugation

Research Areas

Neuronal Cell Markers
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRIK3

References

PMID: 7719709 by Nutt S.L., et al. Molecular characterization of the human EAA5 (GluR7) receptor: a high-affinity kainate receptor with novel potential RNA editing sites.

PMID: 8128318 by Puranam R.S., et al. Chromosomal localization of gene for human glutamate receptor subunit-7.