GRID2 Antibodies

AND GRID2 ELISA kits, GRID2 Proteins

Many biological assays use antibodies to detect GRID2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRID2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRID2 antibodies...

We validate the specificity of these antibodies to GRID2 by testing them on tissues known to express GRID2 positively and negatively. Browse below to find the GRID2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: GRIK2

GRID2 Infographic by Boster Bio

All GRID2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GRID2 Antibody

7 Q&As

Human, Mouse, Rat

IF, WB

$360
Cat # A05305
100 µl

Anti-GRID2 Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A05305-2
100 μg/vial

GRID2 (NM_001510) Human Over-expression Lysate

Human

$960
Cat # LS002895
100 µg

GRID2 Overview

Facts about Glutamate receptor ionotropic, delta-2.

GRID2 3D structure. Source: alphafold

Glutamate receptor ionotropic, delta-2 (GRID2)

Receptor for glutamate.
L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine- dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex (PubMed:27418511).

Gene Information

Human
Gene Name:	GRID2
Uniprot:	O43424
Entrez:	2895

Family

Belongs to:

glutamate-gated ion channel (TC 1.A.10.1) family

Alternative Names

B230104L07Rik; cpr; creeper; gluR delta-2 subunit; GLURD2; GluRdelta2; glutamate receptor delta-2 subunit; glutamate receptor, ionotropic, delta 2; GRID2; ho; hotfoot; Lc; lurcher; minisatellite 10ac detected by probe MMS10; MMS10-AC; Ms10ac; nmf408; SCAR18; tpr

Molecular Weight

Mass (kDA):
113.356 kDA

Genomic Context


Human

Location:	4q22.1-q22.2
Sequence:	4; NC_000004.12 (92303622..93810415)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Diseases

Ataxia
Nerve Degeneration
Malignant Neoplasms
Neoplasms
Atrophy
Cytopathic Effect
Cerebellar Ataxia
Genomic Instability
Depressive Disorder
Cerebellar Diseases
Endometrial Polyp

Endometrial Carcinoma
Movement Disorders
Varicosity
Malignant Neoplasm Of Brain
Sensation Disorders
Carcinoma

Pathways

Cell Death
Autophagy
Bioluminescence
Transport
Prepulse Inhibition
Dendrite Development
Synaptic Transmission
Endocytosis
Oxidative Phosphorylation

Nerve Development
Mitochondrial Fission
Cell Growth
Innervation

PTMs

Phosphorylation

Research Areas

Neuronal Cell Markers
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRID2

References

PMID: 9465309 by Hu W., et al. The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22.

PMID: 27418511 by Elegheert J., et al. Structural basis for integration of GluD receptors within synaptic organizer complexes.