Glutamate receptor 4 Antibodies

Glutamate receptor 4 (GRIA4)

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Gene Information

Human
Gene Name:	GRIA4
Uniprot:	P48058
Entrez:	2893

Family

Belongs to:
glutamate-gated ion channel (TC 1.A.10.1) family

Alternative Names

AMPA-selective glutamate receptor 4; GluA4; GluR4; gluR-4; GLUR4C; GLUR4gluR-D; GLURD; GluR-D; glutamate receptor 4; Glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4

Molecular Weight

Mass (kDA):
100.871 kDA

Genomic Context

Human
Location:	11q22.3
Sequence:	11; NC_000011.10 (105609540..105982092)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression.

Diseases

• Schizophrenia
• Absence Epilepsy
• Epilepsy
• Ataxia Telangiectasia
• Nervousness
• Idiopathic Generalized Epilepsy
• Epilepsy, Generalized
• Ataxia
• Communicable Diseases
• Aneuploidy
• Manic

• Neoplasms
• Pain
• Chromosome Breakage
• Lymphoma
• Dysequilibrium Syndrome

Pathways

• Pathogenesis
• Localization
• Response To Iloperidone
• Cellular Localization
• Cell Adhesion
• Gastrulation
• Dna Hypermethylation
• Prepulse Inhibition
• Fertilization
• Dna Methylation

• Immune Response
• Synaptic Transmission
• Methylation
• Response To Risperidone

PTMs

• Demethylation

• Reduction

• Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRIA4

Steven Boster Bio - Best Uses Of The GRIA4 Marker

Have you ever wondered who Steven Boster is? Are you curious about His hobbies, childhood, and his favorite games? If so, you're in the right place! This article covers Steven's background, along with some of His favorite books, movies, and games. You will also find out about Steven's favorite uses of the GRIA4 marker including bio-tagging, DNA fingerprinting, and DNA fingerprinting.

Steven Boster's history

Steve Boster passed away on Sunday, June 26, 2022. He was a native of Joliet. He was the only child of Evelyn Meier Boster and James Meier Boster. He served in the Army as a veteran and worked for many years as a salesperson. He was also a Concordia Hall member in Staunton, VA. His nieces, nephews, and great-grandchildren are also survivors.

Steve Boster was a man who loved his family. His sons were his joy and pride. He loved to sing in a low voice in front of his family members and friends. He loved auto racing. He was the one who called when his car stopped working at 2 a.m.; he would also show up for appointments even in sub-freezing temperatures. Boster also showed generosity to his friends and treated them as if they were family.