GRB2 Antibodies

AND GRB2 ELISA kits, GRB2 Proteins

Many biological assays use antibodies to detect GRB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRB2 antibodies...

We validate the specificity of these antibodies to GRB2 by testing them on tissues known to express GRB2 positively and negatively. Browse below to find the GRB2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRB2 Infographic by Boster Bio

All GRB2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GRB2 Monoclonal Antibody

16 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M00351
100 μl

Human GRB2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP62993
Starting from 20ug

Anti-GRB2 Antibody (Y209)

Human

IHC-P, WB

$299
Cat # A00351
80 µl

Anti-GRB2 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A00351-1
100 μg/vial

GRB2 (NM_002086) Human Over-expression Lysate

Human

$628
Cat # LS002885
100 µg

Anti-GRB2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M00351-2
100 µl/vial

GRB2 (Phospho-Ser159) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2598
1 kit, containing two 96-well plates and all necessary reagents

GRB2 Overview

Facts about Growth factor receptor-bound protein 2.

GRB2 3D structure. Source: alphafold

Growth factor receptor-bound protein 2 (GRB2)

Adapter protein that provides a critical connection between cell surface growth factor receptors and the Ras signaling pathway. .

Gene Information

Human
Gene Name:	GRB2
Uniprot:	P62993
Entrez:	2885

Family

Belongs to:

GRB2/sem-5/DRK family

Alternative Names

abundant SRC homology; Adapter protein GRB2; ASH; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; GRB2; Grb3-3; growth factor receptor-bound protein 2; growth factor receptor-bound protein 3; HT027; MST084; MSTP084; NCKAP2; Protein Ash; SH2/SH3 adapter GRB2

Molecular Weight

Mass (kDA):
25.206 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (75318076..75405709, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Endosome. Golgi apparatus.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Cell Transformation, Neoplastic
Leukemia
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Myeloid Leukemia
Myeloid Leukemia, Chronic
Metaplastic Cell Transformation
Neoplasm Metastasis
Cell Invasion

Malignant Paraganglionic Neoplasm
Lymphoma
Tumor Angiogenesis
Janiceps
Hyperplasia
Chimera Disorder
Nervousness

Pathways

Cell Proliferation
Cell Growth
Localization
Cell Activation
Endocytosis
Cell Cycle
Cell Migration
Pathogenesis
T Cell Activation
Cell Adhesion
Cell Death
Secretion
Angiogenesis

Cell Motility
Cell Differentiation
Transport
Rna Interference
Cell Development
Mitosis
Intracellular Signal Transduction

PTMs

Phosphorylation
Dephosphorylation
Ubiquitination
Cleavage
Myristoylation
Biotinylation
Reduction
Palmitoylation
Glycosylation

Oxidation
Ribosylation
Farnesylation
Methylation
Hydroxylation
Prenylation
Acylation
Iodination
Acetylation

Deglycosylation

Research Areas

Angiogenesis
Breast Cancer
Cancer
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRB2

References

PMID: 1322798 by Lowenstein E.J., et al. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

PMID: 1384039 by Matuoka K., et al. Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries.