GRAP2 Antibodies

AND GRAP2 ELISA kits, GRAP2 Proteins

Many biological assays use antibodies to detect GRAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRAP2 antibodies...

We validate the specificity of these antibodies to GRAP2 by testing them on tissues known to express GRAP2 positively and negatively. Browse below to find the GRAP2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRAP2 Infographic by Boster Bio

All GRAP2 Products

Product

Figures

Specificity

Applications

Price

Anti-GRAP2 Purified Monoclonal Antibody

Human

Flow Cytometry, IP, WB

$298
Cat # M04115
0.1 mg

Anti-Gads (N158) GRAP2 Antibody

Human, Mouse, Rat

$405
Cat # A04115
100ul

Human GRAP2 Recombinant Protein

SDS-PAGE

$265
Cat # PROTO75791
Starting from 10ug

Anti-GRAP2 Mouse Monoclonal Antibody [Clone ID: OTI1G2]

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M04115-1
100 µl

GRAP2 (NM_004810) Human Over-expression Lysate

Human

$628
Cat # LS009402
100 µg

GRAP2 Overview

Facts about GRB2-related adapter protein 2.

GRAP2 3D structure. Source: alphafold

GRB2-related adapter protein 2 (GRAP2)

Interacts with SLP-76 to regulate NF-AT activation.
Binds to tyrosine-phosphorylated shc.

Gene Information

Human
Gene Name:	GRAP2
Uniprot:	O75791
Entrez:	9402

Family

Belongs to:

GRB2/sem-5/DRK family

Alternative Names

Adapter protein GRID; GADS; GADSSH3-SH2-SH3 adapter Mona; GRAP2; GRB2L; GRB-2-like protein; GRB2-related adapter protein 2; GRB2-related adaptor protein 2; GRB2-related protein with insert domain; GRBLG; GRBLGGRAP-2; GRBX; Grf40 adapter protein; Grf40; grf-40; GRID; GRIDGRPL; Growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; GRPL; Hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; Mona; P38; Protein GADS; SH3-SH2-SH3 adaptor molecule

Molecular Weight

Mass (kDA):
37.909 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (39901073..39973721)

Subcellular Localizations

Nucleus. Cytoplasm. Endosome.

Diseases

Neoplasms
Carcinoma
Malignant Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Tissue Adhesions
Retinoblastoma
Leukemia
Neoplasm Invasiveness
Myeloid Leukemia
Mammary Neoplasms
Liver Carcinoma
Medullary Carcinoma Of Thyroid

Diabetes Mellitus
Carcinogenesis
Cell Invasion
Schizophrenia
Hyperplasia
Malignant Neoplasm Of Thyroid
Neoplasm Metastasis

Interacting Proteins

EGFR
ERBB2
GAREM1
Kcnma1
KIT

LCP2
LNX1
PTPN23
SPRY2
STAMBP

ZSCAN21

Pathways

Cell Activation
T Cell Activation
Cell Proliferation
Cell Growth
Secretion
Cell Cycle
Reverse Transcription
Intracellular Signal Transduction
Cytokine Production
Cell Death
Pathogenesis
Cell Adhesion
Hyperphosphorylation

Platelet Activation
Mammary Gland Development
Cell Cycle Arrest
Cell Maturation
Fermentation
Translation
Telomere Maintenance

PTMs

Phosphorylation

Cleavage

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRAP2

References

PMID: 9878555 by Qiu M., et al. Molecular cloning and expression of human grap-2, a novel leukocyte- specific SH2- and SH3-containing adaptor-like protein that binds to gab-1.

PMID: 10209041 by Law C.-L., et al. GrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activation.