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GRAP Antibodies

AND GRAP ELISA kits, GRAP Proteins

Many biological assays use antibodies to detect GRAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRAP antibodies...

We validate the specificity of these antibodies to GRAP by testing them on tissues known to express GRAP positively and negatively. Browse below to find the GRAP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRAP Infographic by Boster Bio

GRAP protein infographic

All GRAP Products

Product

Figures

Specificity

Applications

Price

Anti-GRB2-related adapter protein Grap Antibody

4 Q&As

Human, Mouse, Rat

WB

$399
Cat # A09913-1
100μl

Anti-GRB2-related adapter protein Grap Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A09913
100ul

GRAP (NM_006613) Human Over-expression Lysate

Human

$628
Cat # LS010750
100 µg

GRAP Overview

Facts about GRB2-related adapter protein.

GRAP 3D structure

GRAP 3D structure. Source: alphafold

GRB2-related adapter protein (GRAP)

Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. .

Gene Information

Human
Gene Name:	GRAP
Uniprot:	Q13588
Entrez:	10750

Gene Information

Family

Belongs to:

GRB2/sem-5/DRK family

Family

Alternative Names

GRB2-related adapter protein; GRB2-related adaptor protein; growth factor receptor-bound protein 2-related adaptor protein; MGC64880

Molecular Weight

Mass (kDA):
25.337 kDA

Molecular Weight

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (19020656..19046957, complement)

Subcellular Localizations

Membrane; Peripheral membrane protein. Cell junction, synapse. Localizes at the presynaptic terminal.

Subcellular Localization

Diseases

Neoplasms
Hypospadias
Pathologic Fistula
Nervousness
Acquired Phimosis
Urinary Fistula
Cell Transformation, Neoplastic
Aneurysm
Brain Ischemia
Diabetic Nephropathy
Dizziness
Hypoxia

Urethral Fistula
Neoplasms, Fibrous Tissue
Carcinoma
Solitary Fibrous Tumor
Urethral Meatus Stenosis
Hemorrhage

Disease

Interacting Proteins

RBPMS
TRIM21

Interacting Proteins

Pathways

Cell Activation
Induction Of Apoptosis
T Cell Activation
Mitosis
Aging
Immune Response
Adaptive Immune Response
Intracellular Signal Transduction
Regulation Of B Cell Activation
Endocytosis
B Cell Activation
Localization
Reflex

Fermentation
Negative Regulation Of B Cell Activation
Cellular Localization
Cell Cycle
Interleukin-2 Production
Pathogenesis
Lymphocyte Proliferation

Pathways

PTMs

Phosphorylation

Cleavage

Palmitoylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRAP

References

PMID: 8647802 by Feng G.-S., et al. Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway.

PMID: 9489702 by Zhang W., et al. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.