GPSM1 Antibodies

AND GPSM1 ELISA kits, GPSM1 Proteins

Many biological assays use antibodies to detect GPSM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPSM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPSM1 antibodies...

We validate the specificity of these antibodies to GPSM1 by testing them on tissues known to express GPSM1 positively and negatively. Browse below to find the GPSM1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPSM1 Infographic by Boster Bio

All GPSM1 Products

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Product

Figures

Specificity

Applications

Price

Anti-AGS3 GPSM1 Antibody

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A04971
100ul

GPSM1 (NM_001145638) Human Recombinant Protein

$1062
Cat # PROTQ86YR5
20 µg

GPSM1 Overview

Facts about G-protein-signaling modulator 1.

GPSM1 3D structure. Source: alphafold

G-protein-signaling modulator 1 (GPSM1)

Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors.

Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells.

Gene Information

Human
Gene Name:	GPSM1
Uniprot:	Q86YR5
Entrez:	26086

Family

Belongs to:

GPSM family

Alternative Names

1810037C22Rik; C. elegans); DKFZp727I051; G-protein signaling modulator 1; G-protein-signaling modulator 1

Molecular Weight

Mass (kDA):
74.51 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136327539..136359605)

Tissue Specificity

Expressed in intestinal cells.

Subcellular Localizations

Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Diseases

Substance Withdrawal Syndrome
Addictive Behavior
Substance-related Disorders
Malignant Neoplasms
Polycystic Kidney Diseases
Kidney Diseases
Reperfusion Injury
Injury To Kidney
Dysplasia

Pertussis
Chimera Disorder
Cell Transformation, Neoplastic
Nerve Degeneration

Interacting Proteins

KANK2

Pathways

Localization
Cell Proliferation
Cell Division
Cellular Process
Sensitization
Macroautophagy
Cell Cycle
Epithelial Cell Proliferation
Bioluminescence
Regulation Of Cell Cycle
Cell Migration
Mitosis
Brain Development

Neurogenesis
Keratinocyte Differentiation
Cytokinesis
Regeneration
Asymmetric Cell Division
Neural Precursor Cell Proliferation
Cellular Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPSM1

References

PMID: 11024022 by Natochin M., et al. AGS3 inhibits GDP dissociation from galpha subunits of the Gi family and rhodopsin-dependent activation of transducin.

PMID: 12642577 by Pattingre S., et al. The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.