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- Table of Contents
Facts about Probable G-protein coupled receptor 88.
.
Human | |
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Gene Name: | GPR88 |
Uniprot: | Q9GZN0 |
Entrez: | 54112 |
Belongs to: |
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G-protein coupled receptor 1 family |
G protein coupled receptor 88; G protein-coupled receptor 88; GPR88; G-protein coupled receptor 88; probable G-protein coupled receptor 88; STRG; Striatum-specific G-protein coupled receptor
Mass (kDA):
40.246 kDA
Human | |
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Location: | 1p21.2 |
Sequence: | 1; NC_000001.11 (100538139..100542021) |
Expressed predominantly in the striatum.
Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. During cortical lamination, subcellular location shifts, on the day of birth, from expression at the plasma membrane and in the cytoplasm to the nuclei of neurons. This intranuclear localization remains throughout adulthood.
PMID: 11056049 by Mizushima K., et al. A novel G-protein-coupled receptor gene expressed in striatum.
PMID: 27123486 by Alkufri F., et al. Deleterious mutation in GPR88 is associated with chorea, speech delay, and learning disabilities.