GPR78 Antibodies

AND GPR78 ELISA kits, GPR78 Proteins

Many biological assays use antibodies to detect GPR78, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR78 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR78 antibodies...

We validate the specificity of these antibodies to GPR78 by testing them on tissues known to express GPR78 positively and negatively. Browse below to find the GPR78 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR78 Infographic by Boster Bio

All GPR78 Products

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Product

Figures

Specificity

Applications

Price

Anti-G-protein coupled receptor 78 GPR78 Antibody

Human

ELISA, WB

$380
Cat # A11858
100ul

GPR78 (NM_080819) Human Over-expression Lysate

Human

$628
Cat # LS027201
100 µg

GPR78 Overview

Facts about G-protein coupled receptor 78.

GPR78 3D structure. Source: alphafold

G-protein coupled receptor 78 (GPR78)

Orphan receptor. Displays a significant level of constitutive activity.

Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. .

Gene Information

Human
Gene Name:	GPR78
Uniprot:	Q96P69
Entrez:	27201

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 78; GPR78; G-protein coupled receptor 78

Molecular Weight

Mass (kDA):
39.332 kDA

Genomic Context


Human

Location:	4p16.1
Sequence:	4; NC_000004.12 (8580392..8590023)

Tissue Specificity

High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Endoplasmic Reticulum Stress
Malignant Neoplasms
Mood Disorders
Bone Neoplasms
Carcinoma
Injury To Liver
Chondrosarcoma
Neoplasms
Encephalitis
Pituitary Diseases
Dysequilibrium Syndrome
Bipolar Disorder

Fatty Liver
Infective Disorder
Japanese Encephalitis
Malignant Neoplasm Of Prostate
Liver Carcinoma
Malignant Neoplasm Of Skin

Pathways

Cell Death
Senescence
Sensitization
Brain Development

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

GPCR
Lipid and Metabolism
Unfolded Protein Response

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR78

References

PMID: 11574155 by Lee D.K., et al. Discovery and mapping of ten novel G protein-coupled receptor genes.

PMID: 17363172 by Jones P.G., et al. Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78.