C5AR2 Antibodies

AND C5AR2 ELISA kits, C5AR2 Proteins

Many biological assays use antibodies to detect C5AR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C5AR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C5AR2 antibodies...

We validate the specificity of these antibodies to C5AR2 by testing them on tissues known to express C5AR2 positively and negatively. Browse below to find the C5AR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C5AR2 Infographic by Boster Bio

All C5AR2 Products

Product

Figures

Specificity

Applications

Price

Anti-C5ARL C5AR2 Antibody

Human

ELISA, WB

$380
Cat # A05083
100ul

C5L2 (C5AR2) (NM_018485) Human Over-expression Lysate

Human

$628
Cat # LS027202
100 µg

C5AR2 Overview

Facts about C5a anaphylatoxin chemotactic receptor 2.

C5AR2 3D structure. Source: alphafold

C5a anaphylatoxin chemotactic receptor 2 (C5AR2)

Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.

Gene Information

Human
Gene Name:	C5AR2
Uniprot:	Q9P296
Entrez:	27202

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

C5a anaphylatoxin chemotactic receptor C5L2; C5L2; C5L2G-protein coupled receptor 77; G protein-coupled receptor 77; G protein-coupled receptor C5L2; GPF77; GPR77

Molecular Weight

Mass (kDA):
36.08 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (47331614..47347329)

Tissue Specificity

Frontal cortex, hippocampus, hypothalamus, pons and liver.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Inflammation
Systemic Infection
Diabetes Mellitus
Insulin Resistance
Septic Shock
Obesity
Hyperlipidemia
Hyperlipidemia, Familial Combined
Combined Hyperlipidaemia
Diabetes Mellitus, Non-insulin-dependent
Neurodegenerative Disorders
Inflammatory Response

Cardiovascular Diseases
Asthma
Nerve Degeneration
Hypertensive Disease
Mutation Abnormality
Lung Diseases
Lung Diseases, Obstructive

Pathways

Transport
Glucose Transport
Complement Activation
Chemotaxis
Pathogenesis
Endocytosis
Inflammatory Response
Regeneration
Secretion
Cytolysis
Cell Migration
Chemokine Production
Parturition

Insulin Secretion
Immune Response
Hypersensitivity
Sensitization
Cytokine Production
Tissue Regeneration
Cell Death

PTMs

Acylation
Phosphorylation

Cleavage
Oxidation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C5AR2

References

PMID: 11090875 by Ohno M., et al. A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells.

PMID: 11165367 by Lee D.K., et al. Identification of four novel human G protein-coupled receptors expressed in the brain.