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- Table of Contents
Facts about 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor.
Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. .
Human | |
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Gene Name: | GPR31 |
Uniprot: | O00270 |
Entrez: | 2853 |
Belongs to: |
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G-protein coupled receptor 1 family |
12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; GPR31; HETER1; probable G-protein coupled receptor 31
Mass (kDA):
35.075 kDA
Human | |
---|---|
Location: | 6q27 |
Sequence: | 6; NC_000006.12 (167155247..167157980, complement) |
Cell membrane; Multi-pass membrane protein.
PMID: 9205127 by Zingoni A., et al. Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.
PMID: 21712392 by Guo Y., et al. Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.