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GPR31 Antibodies

AND GPR31 ELISA kits, GPR31 Proteins

Many biological assays use antibodies to detect GPR31, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR31 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR31 antibodies...

We validate the specificity of these antibodies to GPR31 by testing them on tissues known to express GPR31 positively and negatively. Browse below to find the GPR31 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR31 Infographic by Boster Bio

GPR31 protein infographic

All GPR31 Products

Product

Figures

Specificity

Applications

Price

Anti-GPR31 Antibody

Human

ELISA, WB

$380
Cat # A14413
100ul

GPR31 Overview

Facts about 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor.

GPR31 3D structure

GPR31 3D structure. Source: alphafold

12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor (GPR31)

High-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive mobile access to the subendothelial matrix, which is a critical step for extravasation or metastasis.

Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B. .

Gene Information

Human
Gene Name:	GPR31
Uniprot:	O00270
Entrez:	2853

Gene Information

Family

Belongs to:

G-protein coupled receptor 1 family

Family

Alternative Names

12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; GPR31; HETER1; probable G-protein coupled receptor 31

Molecular Weight

Mass (kDA):
35.075 kDA

Molecular Weight

Genomic Context


Human

Location:	6q27
Sequence:	6; NC_000006.12 (167155247..167157980, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Cell Invasion
Skin Diseases, Vascular
Systemic Infection
Listeriosis
Extravasation
Vasculitis

Disease

Pathways

Localization

Pathways

PTMs

Glycoprotein

Research Areas

GPCR

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR31

References

PMID: 9205127 by Zingoni A., et al. Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.

PMID: 21712392 by Guo Y., et al. Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.