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- Table of Contents
Facts about G-protein coupled receptor 22.
May be involved in ciliogenesis (By similarity). .
Human | |
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Gene Name: | GPR22 |
Uniprot: | Q99680 |
Entrez: | 2845 |
Belongs to: |
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G-protein coupled receptor 1 family |
G protein-coupled receptor 22; GPR22; MGC129847; probable G-protein coupled receptor 22
Mass (kDA):
49.265 kDA
Human | |
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Location: | 7q22.3 |
Sequence: | 7; NC_000007.14 (107470057..107476207) |
High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:9073069, PubMed:18539757).
Cell membrane; Multi-pass membrane protein.
PMID: 9073069 by O'Dowd B.F., et al. Cloning and chromosomal mapping of four putative novel human G- protein-coupled receptor genes.
PMID: 18539757 by Adams J.W., et al. Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor.