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- Table of Contents
Facts about GPN-loop GTPase 1.
Types an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
Human | |
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Gene Name: | GPN1 |
Uniprot: | Q9HCN4 |
Entrez: | 11321 |
Belongs to: |
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GPN-loop GTPase family |
ATP(GTP)-binding protein; ATPBD1A; GPN-loop GTPase 1; GTPase; MBD2-interacting protein; MBDin; MBDINXPA binding protein 1; XAB1FLJ51176; XPA-binding protein 1
Mass (kDA):
41.74 kDA
Human | |
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Location: | 2p23.3 |
Sequence: | 2; NC_000002.12 (27628648..27651511) |
Expressed ubiquitously.
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm.
PMID: 11058119 by Nitta M., et al. A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA.
PMID: 11124703 by Stanchi F., et al. Characterization of 16 novel human genes showing high similarity to yeast sequences.