GPM6B Antibodies

AND GPM6B ELISA kits, GPM6B Proteins

Many biological assays use antibodies to detect GPM6B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPM6B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPM6B antibodies...

We validate the specificity of these antibodies to GPM6B by testing them on tissues known to express GPM6B positively and negatively. Browse below to find the GPM6B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPM6B Infographic by Boster Bio

All GPM6B Products

Product

Figures

Specificity

Applications

Price

Anti-GPM6B Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A08051
100ul

GPM6B Overview

Facts about Neuronal membrane glycoprotein M6-b.

GPM6B 3D structure. Source: alphafold

Neuronal membrane glycoprotein M6-b (GPM6B)

May be involved in neural development. Involved in regulation of osteoblast function and bone formation.

Involved in matrix vesicle discharge by osteoblasts; this purpose seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.

Gene Information

Human
Gene Name:	GPM6B
Uniprot:	Q13491
Entrez:	2824

Family

Belongs to:

myelin proteolipid protein family

Alternative Names

glycoprotein M6B; M6b; M6Bneuronal membrane glycoprotein M6-b; MGC17150; MGC54284; protolipid M6B

Molecular Weight

Mass (kDA):
28.989 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (13770922..13938824, complement)

Tissue Specificity

Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Colocalizes with SERT at the plasma membrane.

Diseases

Acute Erythroblastic Leukemia
Pelizaeus-merzbacher Disease
Neoplasms
Tissue Adhesions
Meningioma
Rett Syndrome
Glioblastoma
Brain Neoplasms
Leukodystrophy
Acquired Immunodeficiency Syndrome
Neoplasm Metastasis

Anemia, Sickle Cell
Aicardi's Syndrome
Malignant Neoplasms
Meningeal Neoplasms
Retroviridae Infections
Lymphoma

Pathways

Cell Adhesion
Transport
Intracellular Transport
Cytoskeleton Organization
Translation
Osteoblast Differentiation
Neurogenesis

Serotonin Uptake
Myelination

PTMs

Phosphorylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPM6B

References

PMID: 8661015 by Olinsky S., et al. Chromosomal mapping of the human M6 genes.

PMID: 9674909 by Narayanan V., et al. Mutation analysis of the M6b gene in patients with Rett syndrome.