GP1BB Antibodies

AND GP1BB ELISA kits, GP1BB Proteins

Many biological assays use antibodies to detect GP1BB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GP1BB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GP1BB antibodies...

We validate the specificity of these antibodies to GP1BB by testing them on tissues known to express GP1BB positively and negatively. Browse below to find the GP1BB antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: GP5

GP1BB Infographic by Boster Bio

All GP1BB Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CD42c GP1BB Antibody

Human, Mouse, Rat

$405
Cat # A06258
100ul

GP1BB Overview

Facts about Platelet glycoprotein Ib beta chain.

GP1BB 3D structure. Source: alphafold

Platelet glycoprotein Ib beta chain (GP1BB)

Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. .

Gene Information

Human
Gene Name:	GP1BB
Uniprot:	P13224
Entrez:	2812

Family

Belongs to:

No superfamily

Alternative Names

antigen CD42b-beta; BDPLT1; BS; CD42c; glycoprotein Ib (platelet), beta polypeptide; glycoprotein Ib platelet beta subunit; GP1BB; GPIbb; GPIbbeta; GPIb-Beta; nuclear localization signal deleted in velocardiofacial syndrome; platelet glycoprotein Ib beta chain; platelet membrane glycoprotein Ib beta; truncated platelet membrane glycoprotein Ib beta

Molecular Weight

Mass (kDA):
21.718 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (19723539..19724771)

Tissue Specificity

Expressed in heart and brain.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Hemorrhage
Bleeding Tendency
Bernard-soulier Syndrome
Von Willebrand Disease
Malformations Of Cortical Development
Alloimmunization
Developmental Delay (disorder)
Craniofacial Abnormalities
Angina Pectoris
Coronary Artery Disease
Congenital Anomaly Of Face
Dysplasia

Autistic Disorder
Congenital Heart Defects
Heart Diseases
Congenital Heart Disease
Cortical Dysplasia
Polymicrogyria

Interacting Proteins

GP1BA

Pathways

Translation
Exocytosis
Secretion
Platelet Aggregation

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GP1BB

References

PMID: 3353370 by Lopez J.A., et al. The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.

PMID: 8021244 by Yagi M., et al. Structural characterization and chromosomal location of the gene encoding human platelet glycoprotein Ib beta.