GOSR1 Antibodies

AND GOSR1 ELISA kits, GOSR1 Proteins

Many biological assays use antibodies to detect GOSR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GOSR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GOSR1 antibodies...

We validate the specificity of these antibodies to GOSR1 by testing them on tissues known to express GOSR1 positively and negatively. Browse below to find the GOSR1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GOSR1 Infographic by Boster Bio

All GOSR1 Products

Product

Figures

Specificity

Applications

Price

Anti-GOSR1/Gs28 Antibody

Human, Mouse, Rat

ELISA, WB

$335
Cat # A09064
100ul

GOSR1 (NM_001007024) Human Recombinant Protein

$1249
Cat # PROTO95249
20 µg

GOSR1 Overview

Facts about Golgi SNAP receptor complex member 1.

GOSR1 3D structure. Source: alphafold

Golgi SNAP receptor complex member 1 (GOSR1)

Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport.
It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive variable ) attachment protein receptor.

May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels through inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport.

Gene Information

Human
Gene Name:	GOSR1
Uniprot:	O95249
Entrez:	9527

Family

Belongs to:

GOSR1 family

Alternative Names

golgi integral membrane protein 2; golgi SNAP receptor complex member 1,28 kDa cis-Golgi SNARE p28; Golgi SNARE 28 kDa; GOLIM2; GOS28cis-golgi SNARE; GOS-28GOS28/P28; GOSR1; GS28; GS2828 kDa Golgi SNARE protein; p28

Molecular Weight

Mass (kDA):
28.613 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (30477402..30527592)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type IV membrane protein. Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network (By similarity). Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius).

Diseases

Neoplasms
Urinary Incontinence
Essential Hypertension
Urinary Stress Incontinence
Neurodegenerative Disorders
Stomatitis
Malignant Neoplasm Of Lung
Carcinoma
Malignant Neoplasms
Nervousness
Cerebrovascular Accident
Spots On Skin

Myeloproliferative Syndrome, Transient
Malignant Squamous Cell Neoplasm
Hepatitis
Hepatitis C
Tissue Adhesions
Malignant Neoplasm Of Esophagus
Vesicular Stomatitis

Pathways

Transport
Localization
Vesicle Docking
Cell Adhesion
Ras Protein Signal Transduction
Pigmentation
Positive Regulation Of Fat Cell Differentiation
Sensitization
Reverse Transcription
Translation
Fatty Acid Transport
System Development
Cell Cycle

Regulation Of Fat Cell Differentiation
Regulation Of Mitosis
Cell Differentiation
Lipid Transport
Visual Perception
Vesicle Targeting
Secretory Pathway

PTMs

Phosphorylation
Dephosphorylation

Prenylation
Ubiquitination

Research Areas

Membrane Trafficking and Chaperones

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GOSR1

References

PMID: 9653160 by Mao M., et al. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning.

PMID: 10198168 by Bui T.D., et al. cDNA characterization and chromosomal mapping of human Golgi SNARE GS27 and GS28 to chromosome 17.