GNAQ Antibodies

AND GNAQ ELISA kits, GNAQ Proteins

Many biological assays use antibodies to detect GNAQ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNAQ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNAQ antibodies...

We validate the specificity of these antibodies to GNAQ by testing them on tissues known to express GNAQ positively and negatively. Browse below to find the GNAQ antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GNAQ Infographic by Boster Bio

All GNAQ Products

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Product

Figures

Specificity

Applications

Price

Anti-GNAQ Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9707
100 μg/vial

Anti-GNAQ Antibody Picoband® (monoclonal, 13H4)

6 Q&As

Human, Monkey, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M00898
100 μg/vial

Human GNAQ Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP50148
Starting from 20ug

Anti-GNAQ Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M00898-1
100 μl/vial

GNAQ Overview

Facts about Guanine nucleotide-binding protein G(q) subunit alpha.

GNAQ 3D structure. Source: alphafold

Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell choice and survival and is required to prevent B-cell-dependent autoimmunity.

Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). .

Gene Information

Human
Gene Name:	GNAQ
Uniprot:	P50148
Entrez:	2776

Family

Belongs to:

G-alpha family

Alternative Names

GAQG-ALPHA-q; guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) subunit alpha

Molecular Weight

Mass (kDA):
42.142 kDA

Genomic Context


Human

Location:	9q21.2
Sequence:	9; NC_000009.12 (77716097..78031811, complement)

Tissue Specificity

Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).

Subcellular Localizations

Nucleus. Membrane. Nucleus membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.

Diseases

Melanoma
Neoplasms
Uveal Melanoma
Malignant Neoplasms
Uveal Neoplasms
Melanocytic Nevus
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm
Nevus, Blue
Skin Neoplasms
Cutaneous Melanoma
Metastatic Melanoma

Carcinoma
Nervousness
Ocular Melanoma
Cell Transformation, Neoplastic
Cellular Blue Nevus
Leukemia

Interacting Proteins

ARRB1
IQSEC1
KISS1R
RARA
Trpm8

Pathways

Pathogenesis
Cell Cycle
Localization
Oncogenesis
Enucleation
Cell Proliferation
Secretion
Cell Adhesion
Peripheral B Cell Tolerance Induction
Leukocyte Proliferation
Proteolysis
Neurogenesis
Eating Behavior

Pigmentation
Cell Cycle Arrest
B Cell Selection
Sensitization
Reverse Transcription
System Development
Cell Differentiation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNAQ

References

PMID: 8825633 by Dong Q., et al. Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene.

PMID: 8664309 by Chen B., et al. Human G(alpha q): cDNA and tissue distribution.